{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:41:34Z","timestamp":1762299694048,"version":"3.40.5"},"reference-count":28,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T00:00:00Z","timestamp":1613606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>This study aimed to evaluate the safety and clinical efficacy of external carotid artery (ECA) stenting in patients with ipsilateral internal carotid artery (ICA) occlusion.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>In patients with ICA occlusion, severe ipsilateral ECA stenosis may exacerbate pre\u2010existing cerebral ischemia and cognitive impairment. It remains unclear whether ECA stenting to normalize ECA collaterals to the cerebralis alleviates cerebral ischemia and improves cognitive function.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From January 2008 to June 2019, we retrospectively collected clinical data of 36 consecutive patients with ipsilateral ICA occlusion who had undergone ECA stenting (mean age, 66.7\u2009\u00b1\u20098.3\u2009years; males, <jats:italic>n\u2009=<\/jats:italic> 26 [72.2%]). Neurocognitive test results, including Mini\u2010Mental State Examination (MMSE) and Montreal Cognitive Assessment (MOCA) tests, symptom assessment, and adverse events were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>ECA stenting was successful in all 36 patients. Intra\u2010operatively, six (16.7%) patients experienced hemodynamic depression during balloon dilation and recovered completely within 2\u2009days. Within a 12\u2010month follow\u2010up period, two patients experienced a transient ischemic attack, one patient had a contralateral minor stroke, and 33 patients remained asymptomatic. No other adverse events occurred in the peri\u2010operative or follow\u2010up periods. Compared with baseline, significant MMSE (25.3\u2009\u00b1\u20091.3 vs. 23.6\u2009\u00b1\u20091.7; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) and MOCA (24.1\u2009\u00b1\u20091.3 vs. 22.8\u2009\u00b1\u20091.7; <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) test score improvements were observed 3\u2009months post\u2010operatively and were maintained throughout follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>ECA stenting may improve cerebral ischemia and cognitive function in patients with severe ECA stenosis and ipsilateral ICA occlusion; however, further research is required to support our findings.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29563","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T20:39:38Z","timestamp":1613853578000},"page":"982-987","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["<scp>External<\/scp> carotid artery stenting in patients with ipsilateral internal carotid artery occlusion: Peri\u2010operative and 12\u2010month follow\u2010up"],"prefix":"10.1002","volume":"97","author":[{"given":"Hui","family":"Dong","sequence":"first","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0187-8379","authenticated-orcid":false,"given":"Xiongjing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yubao","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jining","family":"He","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5391-2474","authenticated-orcid":false,"given":"Yu","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1165-7302","authenticated-orcid":false,"given":"Bo","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Runlin","family":"Gao","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Fuwai Hospital National Center for Cardiovascular Disease, Chinese Academy of Medical Sciences and Peking Union Medical College  Beijing 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