{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:44:42Z","timestamp":1780569882778,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T00:00:00Z","timestamp":1619136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective was to evaluate the results of valve\u2010in\u2010valve procedures performed with the Allegra device.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Transcatheter aortic valve implantation to treat degenerated biological aortic valves (valve\u2010in\u2010valve) is an established procedure in most catheterization laboratories, but the results are poorer than procedures done in native aortic stenosis. The Allegra device (Biosensors, Morges, Switzerland) has an excellent design to treat these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients with severely degenerated biological aortic valve treated with the Allegra device in centers from Spain until December 2020 were included (<jats:italic>n<\/jats:italic>\u00a0=\u200929). Hemodynamic results and 30\u2010day clinical outcomes were evaluated. The predominant hemodynamic failure was stenosis in 15, regurgitation in 11, and a combination of both in 3 cases. Time from aortic valve replacement to valve\u2010in\u2010valve procedure was 8.4\u2009\u00b1\u20093.9\u2009years (range 3.3\u201322.1).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After the procedure, maximum and mean trans\u2010valvular gradients were 17.4\u2009\u00b1\u200912.3 and 8.4\u2009\u00b1\u20096.1\u2009mmHg, respectively. Device success was obtained in 28 patients (96.6%). In one patient with a degenerated 19\u2009mm prosthetic valve, mean gradient after the procedure was 22\u2009mmHg. No patients had a para\u2010valvular leak grade &gt;1. There were no deaths during the hospitalization or at 30\u2009days and one patient suffered a stroke.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The Allegra trans\u2010catheter aortic valve offers optimal hemodynamic results in patients with severely degenerated biological aortic valve.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29742","type":"journal-article","created":{"date-parts":[[2021,4,23]],"date-time":"2021-04-23T09:03:18Z","timestamp":1619168598000},"page":"365-370","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Transcatheter aortic valve implantation for degenerated aortic valves: Experience with a new supra\u2010annular device. The Spanish Allegra valve\u2010in\u2010valve (SAVIV) registry"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7179-1426","authenticated-orcid":false,"given":"Ra\u00fal","family":"Moreno","sequence":"first","affiliation":[{"name":"Interventional Cardiology Hospital La Paz, IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9\u2010Antonio","family":"Baz","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Alvaro Cunqueiro  Vigo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Moreu","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Virgen de la Salud  Toledo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Berenguer","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital General de Valencia  Valencia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5200-4650","authenticated-orcid":false,"given":"Ariana","family":"Gonz\u00e1lvez\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital La Paz, IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Galeote","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital La Paz, IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6555-5697","authenticated-orcid":false,"given":"Ubaldo","family":"Hern\u00e1ndez","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Alvaro Cunqueiro  Vigo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom\u00e1s","family":"Cant\u00f3n","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Virgen de la Salud  Toledo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago","family":"Jim\u00e9nez\u2010Valero","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital La Paz, IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6362-7618","authenticated-orcid":false,"given":"Alfonso","family":"Jurado\u2010Rom\u00e1n","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital La Paz, IdiPAZ  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halley","family":"Moya","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Alvaro Cunqueiro  Vigo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"L\u00e1zaro","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Hospital Virgen de la Salud  Toledo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,4,23]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.09.030"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.7246"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.02.029"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.118.007038"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa252"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.06.010"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2019.04.009"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.05.030"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.115.003651"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-18-00861"},{"key":"e_1_2_5_12_1","first-page":"30422","article-title":"Self\u2010expandable transcatheter heart valves for aortic stenosis. Short\u2010term outcome and matched hemodynamic performance","volume":"20","author":"Vera\u2010Vera S","year":"2020","journal-title":"Rev Esp Cardiol"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV8I7A121"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29433"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-20-01291"},{"key":"e_1_2_5_16_1","first-page":"96","article-title":"Time trend in transcatheter aortic valve implantation: an analysis of the Spanish TAVI registry","volume":"2","author":"Jimenez\u2010Quevedo P","year":"2020","journal-title":"REC Interv Cardiol"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.057"},{"key":"e_1_2_5_18_1","article-title":"The risk of valve thrombosis is higher with intra\u2010annular versus supra\u2010annular transcatheter aortic valve prosthesis. A meta\u2010analysis from randomized controlled trials","author":"Moreno R","year":"2021","journal-title":"Clin Res Cardiol"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-17-00844"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-00331"},{"key":"e_1_2_5_21_1","first-page":"180","article-title":"Causes of peri\u2010operative mortality after transcatheter aortic valve implantation: a pooled analysis of 12 studies and 1223 patients","volume":"23","author":"Moreno R","year":"2011","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005216"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29742","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29742","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29742","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:43:32Z","timestamp":1693341812000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,23]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1002\/ccd.29742"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29742","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4,23]]},"assertion":[{"value":"2021-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}