{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T15:25:44Z","timestamp":1768317944578,"version":"3.49.0"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T00:00:00Z","timestamp":1624665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare 5\u2010year angiographic, optical coherence tomography (OCT), and clinical outcomes between patients treated with bioresorbable vascular scaffolds (BVS) and drug\u2010eluting stents (DES).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The EverBio\u20102 trial (Comparison of Everolimus\u2010 and Biolimus\u2010Eluting Coronary Stents with Everolimus\u2010Eluting Bioresorbable Vascular Scaffold) was a single\u2010center, assessor\u2010blinded, randomized controlled trial in which 240 patients were randomly allocated (1:1:1) to BVS, everolimus\u2010eluting (EES) or biolimus\u2010eluting (BES) DES. Clinical follow\u2010up was scheduled up to 5\u2009years. All patients, alive and who did not have repeat revascularization of the target lesion during follow\u2010up were asked to return for angiographic follow\u2010up at 5\u2009years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five\u2010year angiographic follow\u2010up was completed in 122 patients (51%) and OCT analysis was performed in 86 (36%) patients. In\u2010stent late lumen loss was similar in both groups with 0.50\u2009\u00b1\u20090.38\u2009mm in BVS versus 0.58\u2009\u00b1\u20090.36\u2009mm in EES\/BES,<jats:italic>p<\/jats:italic>\u00a0=\u20090.20. Clinical follow\u2010up was complete in 232 patients (97%) at 5\u2009years. The rate of the device\u2010oriented endpoint was 22% in the BVS and 18% in the EES\/BES group (<jats:italic>p<\/jats:italic>\u00a0=\u20090.49). The patient\u2010oriented composite endpoint occurred in 40% of BVS\u2010 and 43% of EES\/BES\u2010treated patients (<jats:italic>p<\/jats:italic>\u00a0=\u20090.72) at 5\u2009years. No acute coronary syndrome due to stent thrombosis was detected after 2\u2009years. Complete BVS strut resorption was observed at 5\u2009years in the OCT subgroup.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Five\u2010year clinical outcomes were similar between BVS and DES patients as well as angiographic outcomes in a selected subgroup. However, a definitive conclusion cannot be drawn because the EverBio\u20102 trial was not powered for clinical and angiographic endpoints at 5\u2009years of follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29837","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T09:38:47Z","timestamp":1624700327000},"page":"523-532","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Five\u2010year angiographic,<scp>OCT<\/scp>and clinical outcomes of a randomized comparison of everolimus and biolimus\u2010eluting coronary stents with everolimus\u2010eluting bioresorbable vascular scaffolds"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1882-9015","authenticated-orcid":false,"given":"Sara","family":"Schukraft","sequence":"first","affiliation":[{"name":"Cardiology University &amp; Hospital Fribourg Fribourg 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