{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T12:32:20Z","timestamp":1784291540725,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T00:00:00Z","timestamp":1629158400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective was to compare outcomes of redo\u2010aortic valve replacement (AVR) via surgical or transcatheter approach in prior surgical AVR with large percentage of prior stentless surgical AVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>With the introduction of transcatheter aortic valve replacement (TAVR), patients with increased surgical risks now have an alternative to redo surgical AVR (SAVR), known as valve\u2010in\u2010valve (ViV) TAVR. Stentless prosthetic aortic valves present a more challenging implantation for ViV\u2010TAVR given the lack of structural frame.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We performed a retrospective study of 173 subjects who have undergone SAVR (N\u00a0=\u00a0100) or ViV\u2010TAVR (N\u00a0=\u00a073) in patients with prior surgical AVR at Wake Forest Baptist Medical Center from 2009 to 2019. Our study received the proper ethical oversight.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average ages in redo\u2010SAVR and ViV\u2010TAVR groups were 58.03\u2009\u00b1\u200913.86 and 66.57\u2009\u00b1\u200913.44\u2009years, respectively (<jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.0001). The redo\u2010SAVR had significantly lower STS (2.78\u2009\u00b1\u20092.09 and 4.68\u2009\u00b1\u20095.51, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.01) and Euroscores (4.32\u2009\u00b1\u20092.98 and 7.51\u2009\u00b1\u20098.24, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.05). The redo\u2010SAVR group had higher percentage requiring mechanical support (8% vs. 0%, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.05) and vasopressors (53% vs. 0%, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.0001), longer length of stay (13.65\u2009\u00b1\u200911.23 vs. 5.68\u2009\u00b1\u20097.64\u2009days, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.0001), and inpatient mortality (16% vs. 2.78%, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.005). At 30\u2010day follow\u2010up, redo\u2010SAVR group had higher rates of acute kidney injury (10% vs. 0%, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.01), however ViV\u2010TAVR group had more new left bundle branch blocks (6.85% vs. 0%, <jats:italic>p\u2009&lt;<\/jats:italic>\u00a00.05). No significant differences regarding re\u2010hospitalization rates, stroke, or death up to 1\u2010year.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although the ViV\u2010TAVR group had higher risk patients, there were significantly fewer procedural complications, shorter length of stay, and similar mortality outcomes up to 1\u2010year follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29921","type":"journal-article","created":{"date-parts":[[2021,8,17]],"date-time":"2021-08-17T11:02:21Z","timestamp":1629198141000},"page":"181-192","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["<scp>Redo\u2010aortic<\/scp> valve replacement in prior stentless prosthetic aortic valves: Transcatheter versus surgical approach"],"prefix":"10.1002","volume":"99","author":[{"given":"Charles H.","family":"Choi","sequence":"first","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diego","family":"Malaver","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward H.","family":"Kincaid","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adrian","family":"Lata","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal","family":"Kon","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Matthew","family":"Belford","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay K.","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Applegate","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6348-0732","authenticated-orcid":false,"given":"David X. M.","family":"Zhao","sequence":"additional","affiliation":[{"name":"Section of Cardiovascular Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"},{"name":"Department of Internal Medicine Wake Forest School of Medicine, Wake Forest Baptist Health System  Winston\u2010Salem North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,17]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2008.09.030"},{"key":"e_1_2_10_3_1","first-page":"991","article-title":"The risk of reoperative heart valve procedures in octogenarian patients","volume":"13","author":"Kirsch M","year":"2004","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2015.04.062"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28039"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.05.022"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.09.001"},{"key":"e_1_2_10_8_1","first-page":"653","article-title":"Redo procedures for degenerated stentless aortic xenografts and the role of valve\u2010in\u2010valve transcatheter techniques","volume":"51","author":"Grubitzsch H","year":"2017","journal-title":"Eur J Cardiothorac Surg"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-16-00303"},{"key":"e_1_2_10_10_1","first-page":"1494","article-title":"Redo aortic valve surgery versus transcatheter valve\u2010in\u2010valve implantation for failing surgical bioprosthetic valves: consecutive patients in a single\u2010center setting","volume":"7","author":"Erlebach M","year":"2015","journal-title":"J Thorac Dis"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.7246"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.104505"},{"key":"e_1_2_10_13_1","first-page":"542","article-title":"Transcatheter aortic valve\u2010in\u2010valve implantation: clinical outcome as defined by VARC\u20102 and postprocedural valve dysfunction according to the primary mode of bioprosthesis failure","volume":"26","author":"St\u00e4hli BE","year":"2014","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2007.04.061"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.114.002079"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivw300"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12520"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2018.02.054"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.10.030"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29921","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29921","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29921","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T06:00:30Z","timestamp":1693202430000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29921"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,17]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1002\/ccd.29921"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29921","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,17]]},"assertion":[{"value":"2020-08-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-05","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}