{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T19:05:21Z","timestamp":1760123121053,"version":"3.40.5"},"reference-count":31,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T00:00:00Z","timestamp":1629417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to investigate whether lipid core plaque (LCP) in the entire stented segment detected by near\u2010infrared spectroscopy\u2010intravascular ultrasound (NIRS\u2010IVUS) could predict procedural myocardial infarction (PMI) in patients undergoing percutaneous coronary artery intervention (PCI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>NIRS\u2010IVUS can identify LCP, described as high lipid core burden index (LCBI). Previously, the highest LCBI contained only in the 4\u2010mm segment (maxLCBI<jats:sub>4mm<\/jats:sub>) was reported to predict PMI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent NIRS\u2010IVUS examination during PCI for coronary artery disease at Chiba University Hospital were included. The extent of LCP in the stented segment derived from NIRS\u2010IVUS analysis was presented as LCBI, maxLCBI<jats:sub>4mm<\/jats:sub>, and LCP area index (LAI), reflecting the total amount of LCP in the entire stented segment calculated as LCBI\u00d7lesion length. PMI was defined as an elevation of creatine kinase MB &gt;\u20093 times upper reference level (URL), and periprocedural myocardial injury (PMInj) was defined as an elevation of troponin I&gt;5 times URL within 12 to 24\u2009h after PCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Out of 141 enrolled patients, PMI occurred in 20 (14.2%) and PMInj occurred in 62 (44.0%) patients. Receiver\u2010operating characteristic curve analysis revealed LAI was the strongest predictor for both PMI and PMInj (area under curve 0.771, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, and 0.717, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, respectively). Multiple logistic regression analysis determined high LAI value as the independent predictor of both PMI and PMInj.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Greater extent of LCP in the entire stented segment detected by NIRS\u2010IVUS was significantly associated with PMI as well as PMInj in patients undergoing PCI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29927","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T15:14:25Z","timestamp":1629472465000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Utility of near\u2010infrared spectroscopy to detect the extent of lipid core plaque leading to periprocedural myocardial infarction"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8217-8990","authenticated-orcid":false,"given":"Takaaki","family":"Matsuoka","sequence":"first","affiliation":[{"name":"Department 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