{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T16:02:46Z","timestamp":1783526566526,"version":"3.55.0"},"reference-count":54,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T00:00:00Z","timestamp":1632528000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>In this study, we use a national database to evaluate post\u2010transcatheter (TAVR)\/surgical aortic valve replacement (SAVR) outcomes stratified using chronic liver disease (CLD).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>In patients undergoing TAVR and SAVR, the surgical risks should be optimized; this includes evaluating hepatic diseases that may pose an operative risk.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>2011\u20132017 National Inpatient Sample was used to select in\u2010hospital TAVR and SAVR cases, which were stratified according to CLD (cirrhosis, hepatitis B\/C, alcoholic\/fatty\/nonspecific liver disease). The cases\u2013controls were matched using propensity score matching and compared with various endpoints.<\/jats:p><\/jats:sec><jats:sec><jats:title>Result<\/jats:title><jats:p>After matching for demographics and comorbidities, for TAVR, 606 and 1818 were with or without CLD; for SAVR, 1353 and 4059 were with and without CLD. In TAVR, there was no differences in mortality (2.81% vs. 2.75% OR 1.02 95% CI 0.58\u20131.78) or length of stay (6.29 vs. 6.44d <jats:italic>p<\/jats:italic>\u00a0=\u00a00.29), and CLD\u2010present patients had marginally increased costs ($228,415 vs. $226,682 <jats:italic>p<\/jats:italic>\u00a0=\u00a00.048). There were no differences in complications. In multivariate, there was no difference in mortality (aOR 1.02 95% CI 0.58\u20131.79). In SAVR, CLD patients had higher mortality (7.98% vs. 3.23% OR 2.60 95% CI 2.00\u20133.38), length of stay (13.3 vs. 11.3\u2009days <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and costs ($273,487 vs. $238,097 <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). CLD patients also had increased respiratory failure (9.02% vs. 7.19% OR 1.28 95% CI 1.03\u20131.59) and bleeding (8.43% vs. 6.33% OR 1.36 95% CI 1.08\u20131.71). In multivariate, CLD had higher mortality (aOR 2.60 95% CI 2.00\u20133.38).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>CLD is associated with higher mortality and complications in patients undergoing SAVR; however, no correlation was found in patients undergoing TAVR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.29952","type":"journal-article","created":{"date-parts":[[2021,9,25]],"date-time":"2021-09-25T14:37:25Z","timestamp":1632580645000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["The clinical impact of chronic liver disease in patients undergoing transcatheter and surgical aortic valve replacement: Systematic analysis of the 2011\u20132017 <scp>US<\/scp> hospital database"],"prefix":"10.1002","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7129-7532","authenticated-orcid":false,"given":"David Uihwan","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology University of Maryland  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Han","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory Hongyuan","family":"Fan","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David Jeffrey","family":"Hastie","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Kwon","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Jung","family":"Lee","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyse Ann","family":"Addonizio","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffi","family":"Karagozian","sequence":"additional","affiliation":[{"name":"Liver Center, Division of Gastroenterology Tufts Medical Center  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.06.076"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.054072"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.02.012"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs304"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.23368"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.05.028"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.08.2146"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.05.063"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.26345"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2017.06.067"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27232"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/jocs.12177"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510290639"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389200043335531"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31646"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25994"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2016.11.096"},{"key":"e_1_2_8_20_1","article-title":"The effect of malnutrition on the infectious outcomes of hospitalized patients with cirrhosis: analysis of the 2011\u20102017 hospital data","volume":"30","author":"Lee DU","year":"2020","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2021.01.005"},{"key":"e_1_2_8_22_1","volume-title":"Introduction to the HCUP National Inpatient Sample (NIS)","author":"Healthcare Cost and Utilization Project (HCUP). 2017","year":"2019"},{"key":"e_1_2_8_23_1","volume-title":"Nationwide Inpatient Sample (NIS) Redesign Final Report","author":"Houchens R","year":"2014"},{"key":"e_1_2_8_24_1","volume-title":"Healthcare Cost And Utilization Project (HCUP) Recommendations for Reporting Trends Using ICD\u20109\u2010CM and ICD\u201010\u2010CM\/PCS Data","author":"Elixhauser A","year":"2017"},{"key":"e_1_2_8_25_1","unstructured":"Centers for Medicare and Medicaid Services.2017ICD\u201010 PCS Code Descriptions.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD10\/Downloads\/2017\u2010PCS\u2010Long\u2010Abbrev\u2010Titles.zip."},{"key":"e_1_2_8_26_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).2017ICD\u201010\u2010CM Code Descriptions.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD10\/Downloads\/2017-ICD10-Code-Descriptions.zip."},{"key":"e_1_2_8_27_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).ICD\u20109\u2010CM and PCS Diagnosis and Procedure Codes Descriptions Version 32.2014. Accessed August 17 2020.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD9ProviderDiagnosticCodes\/Downloads\/ICD-9-CM-v32-master-descriptions.zip"},{"key":"e_1_2_8_28_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).2017ICD\u201010 PCS General Equivalence Mappings (GEMs) \u2013 Procedure Codes.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD10\/Downloads\/2017\u2010GEM\u2010PCS.zip"},{"key":"e_1_2_8_29_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).2017ICD\u201010\u2010CM General Equivalence Mappings (GEMs) \u2013 Diagnosis Codes.https:\/\/www.cms.gov\/Medicare\/Coding\/ICD10\/Downloads\/2017-GEM-DC.zip"},{"key":"e_1_2_8_30_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).ICD\u201010 Definition of Medicare Code Edits V37.2.2020. Accessed August 17 2020.https:\/\/www.cms.gov\/files\/zip\/definition-medicare-code-edits-v372.zip"},{"key":"e_1_2_8_31_1","unstructured":"Centers for Medicare and Medicaid Services (CMS).ICD\u201010 MS\u2010DRG Definitions Manual Files V37.2.2020. Accessed August 17 2020.https:\/\/www.cms.gov\/files\/zip\/icd-10-ms-drg-definitions-manual-files-v372.zip"},{"issue":"1","key":"e_1_2_8_32_1","first-page":"1211","article-title":"Preparing for the ICD\u201010\u2010CM transition: automated methods for translating ICD codes in clinical phenotype definitions","volume":"4","author":"Fung KW","year":"2016","journal-title":"EGEMS (Wash DC)"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1162\/089976603321891864"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/0049124104268644"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-51862-0.50018-6"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28834"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.01.040"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(04)00296-4"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.06.021"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-198610000-00010"},{"issue":"5","key":"e_1_2_8_41_1","first-page":"771","article-title":"Chronic active hepatitis: possible adverse effect of exploratory laparotomy","volume":"68","author":"Hargrove MD","year":"1970","journal-title":"Surgery"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800810928"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw225"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz275"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2739"},{"issue":"9","key":"e_1_2_8_46_1","first-page":"724","article-title":"Advances in transcatheter aortic valve replacement","volume":"16","author":"Ando T","year":"2019","journal-title":"J Geriatr Cardiol"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008232"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2018.02.018"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.046451"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex002"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.01.055"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.84.5.2213"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31193"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365528609034632"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v9.i2.364"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29952","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.29952","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.29952","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,28]],"date-time":"2023-08-28T04:57:34Z","timestamp":1693198654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.29952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,25]]},"references-count":54,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10.1002\/ccd.29952"],"URL":"https:\/\/doi.org\/10.1002\/ccd.29952","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,9,25]]},"assertion":[{"value":"2021-07-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-02","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}