{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T13:03:42Z","timestamp":1771333422618,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T00:00:00Z","timestamp":1648857600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The index of microvascular resistance (IMR) is an established tool to assess the status of coronary microcirculation. However, the need for a pressure wire and hyperemic agents have limited its routine use and have led to the development of angiography\u2010derived pressure\u2010wire\u2010free methods (angiography\u2010derived\u00a0IMR [IMRAngio]). In this review and meta\u2010analysis, we aim to assess the global diagnosis accuracy of IMRAngio versus IMR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review of the literature was performed. Studies directly evaluating IMRAngio versus IMR were considered eligible. Pooled values of diagnostic test and summary receiver operator curve were calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Seven studies directly comparing IMRAngio versus IMR were included (687 patients; 807 vessels). Pooled sensitivity, specificity, +likelihood ratio (LR), and \u2212LR were 82%, 83%, 4.5, and 0.26 respectively. Pooled accuracy was 83% while pooled positive predictive value\u00a0and negative predictive value were 76% and 85%, respectively. Comparable results were obtained when analyzing by clinical scenario (acute and nonacute coronary syndromes).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>IMRAngio shows a good diagnostic performance for the prediction of abnormal IMR.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30174","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:03:30Z","timestamp":1648926210000},"page":"2018-2025","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Angiography\u2010derived versus invasively\u2010determined index of microcirculatory resistance in the assessment of coronary microcirculation: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3025-8251","authenticated-orcid":false,"given":"Estefania","family":"Fern\u00e1ndez\u2010Peregrina","sequence":"first","affiliation":[{"name":"Division of Interventional Cardiology MedStar Washington Hospital Center  Washington District of Columbia USA"},{"name":"Department of Medicine Universitat Aut\u00f3noma de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5100-0471","authenticated-orcid":false,"given":"Hector M.","family":"Garcia\u2010Garcia","sequence":"additional","affiliation":[{"name":"Division of Interventional Cardiology MedStar Washington Hospital Center  Washington District of Columbia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3176-6191","authenticated-orcid":false,"given":"Jordi","family":"Sans\u2010Rosello","sequence":"additional","affiliation":[{"name":"Division of Interventional Cardiology MedStar Washington Hospital Center  Washington District of Columbia USA"},{"name":"Department of Medicine Universitat Aut\u00f3noma de Barcelona  Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Sanz\u2010Sanchez","sequence":"additional","affiliation":[{"name":"Departamento de Cardiolog\u00eda Intervencionista Hospital de La Fe  Valencia Spain"},{"name":"Centro de Investigacion Biomedica en Red (CIBERCV)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafail","family":"Kotronias","sequence":"additional","affiliation":[{"name":"Oxford Heart Centre, NIHR Biomedical Research Centre Oxford University Hospitals  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Scarsini","sequence":"additional","affiliation":[{"name":"Department of Medicine,\u00a0Division of Cardiology University of Verona  Verona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Echavarria\u2010Pinto","sequence":"additional","affiliation":[{"name":"Facultad de Medicina, Hospital General ISSSTE Quer\u00e9tano Universidad Aut\u00f3noma de Quer\u00e9tano  Santiago de Quer\u00e9tano Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2805-8090","authenticated-orcid":false,"given":"Matteo","family":"Tebaldi","sequence":"additional","affiliation":[{"name":"Cardiovascular Institute Azienda Ospedaliera Univertaria S. Anna Ferrara Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni L.","family":"De Maria","sequence":"additional","affiliation":[{"name":"Oxford Heart Centre, NIHR Biomedical Research Centre Oxford University Hospitals  Oxford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000080700.98607.D1"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.000298"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa503"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005361"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000128669.99355.CB"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.603522"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00003.2012"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-155-8-201110180-00009"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.942"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-020-01831-7"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8887369"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.605356"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.05.027"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-021-02254-8"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29863"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.717114"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.02.014"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-14-0364"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000670"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.112.969048"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.09.006"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2018.02.018"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.08.062"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.04.009"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30174","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.30174","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30174","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T08:59:17Z","timestamp":1692608357000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,2]]},"references-count":24,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/ccd.30174"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30174","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,2]]},"assertion":[{"value":"2021-10-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}