{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T00:26:47Z","timestamp":1788395207466,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T00:00:00Z","timestamp":1649894400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The preferred approach for transcatheter aortic valve replacement (TAVR) is transfemoral. There has been widespread adoption of the Perclose Proglide<jats:sup>TM<\/jats:sup> device for vascular closure. Typically, two devices are deployed before upsizing the access sheath in the \u201cpreclose technique.\u201d Prior investigations have compared the use of a single device versus double device technique, but none have shown significant clinical benefit to either approach.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five hundred and six\u00a0patients underwent transfemoral TAVR (TF\u2010TAVR) with single or double Perclose devices for vascular closure from July 2015 to February 2020. A retrospective review was conducted, and propensity\u2010matched analyses were used to account for differences in baseline characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the matched analysis, there were 251 patients in the single Perclose group and 238 in the double. There was a statistically significant improvement in overall procedural success using the single closure device (94.6% vs. 88.5%, <jats:italic>p<\/jats:italic>\u2009=\u20090.009)\u00a0This was defined as intraprocedural hemostatic control, lack of contrast extravasation, arterial dissection, occlusion, or stenosis &gt;50% in the final crossover angiogram, as well as unimpaired limb perfusion without claudication throughout the index hospitalization. There was also a significant improvement in arterial dissection rates (0.6% vs.\u00a04.6%, <jats:italic>p<\/jats:italic>\u2009=\u20090.004), stenosis &gt;50% (1.3% vs. 4.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.028), and Valve Academic Research Consortium major vascular complications (1.8% vs. 4.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.038).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A single Perclose device is a safe means of vascular closure during TF\u2010TAVR and may have important clinical benefits compared to the commonly used two\u2010device technique.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30176","type":"journal-article","created":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T09:12:07Z","timestamp":1649927527000},"page":"2125-2130","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Single versus double Perclose techniques for vascular closure during transfemoral transcatheter aortic valve replacement"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0732-5281","authenticated-orcid":false,"given":"John","family":"Hollowed","sequence":"first","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Akhondi","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Rabbani","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damla","family":"Oncel","sequence":"additional","affiliation":[{"name":"David Geffen School of Medicine University of California Los Angeles California Los Angeles USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Suh","sequence":"additional","affiliation":[{"name":"Division of Cardiology Riverside Medical Clinic Riverside California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim","family":"Rafique","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray","family":"Kwon","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4705-0262","authenticated-orcid":false,"given":"Peyman","family":"Benharash","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Shemin","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olcay","family":"Aksoy","sequence":"additional","affiliation":[{"name":"Division of Cardiology, David Geffen School of Medicine University of California Los Angeles Los Angeles California 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and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30176","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.30176","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T08:58:57Z","timestamp":1692608337000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,14]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["10.1002\/ccd.30176"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30176","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,14]]},"assertion":[{"value":"2021-12-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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