{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:42:04Z","timestamp":1777678924825,"version":"3.51.4"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T00:00:00Z","timestamp":1652313600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>Transcatheter aortic valve implantation (TAVI) has proved beneficial in patients with severe aortic stenosis, especially when second\u2010generation devices are used. We aimed at reporting our experience with Navitor, a third\u2010generation device characterized by intrannular, large cell, and cuffed design, as well as high deliverability and minimization of paravalvular leak. Between June and December 2021, a total of 39 patients underwent TAVI with Navitor, representing 20% of all TAVI cases. Mean age was 80.0\u2009\u00b1\u20096.7 years, and 14 (36.8%) women were included. Severe aortic stenosis was the most common indication to TAVI (37 [97.4%] cases), whereas 2 (5.3%) individuals were at low surgical risk. Device and procedural success was obtained in all patients, with a total hospital stay of 6.6\u2009\u00b1\u20094.5 days. One (2.9%) patient required permanent pacemaker implantation, but no other hospital events occurred. At 1\u2010month follow\u2010up, a cardiac death was adjudicated in an 87\u2010year\u2010old man who had been at high surgical risk. Echocardiographic follow\u2010up showed no case of moderate or severe aortic regurgitation, with mild regurgitation in 18 (47%), and none or trace regurgitation in 20 (53%). The Navitor device, thanks to its unique features, is a very promising technology suitable to further expand indications and risk\u2010benefit profile of TAVI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30179","type":"journal-article","created":{"date-parts":[[2022,5,12]],"date-time":"2022-05-12T14:31:45Z","timestamp":1652365905000},"page":"114-119","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Transcatheter aortic valve implantation with the novel\u2010generation Navitor device: Procedural and early outcomes"],"prefix":"10.1002","volume":"100","author":[{"given":"Nicola","family":"Corcione","sequence":"first","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Berni","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit,\u00a0Sant'Andrea University Hospital Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Ferraro","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Emodinamica, Santa Lucia Hospital San Giuseppe Vesuviano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Morello","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6390-0178","authenticated-orcid":false,"given":"Michele","family":"Cimmino","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Albanese","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Emodinamica, Santa Lucia Hospital San Giuseppe Vesuviano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luisa","family":"Nestola","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"Bardi","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martino","family":"Pepe","sequence":"additional","affiliation":[{"name":"Department of Emergency and Organ Transplantation (DETO), Cardiovascular Diseases Section University of Bari Aldo Moro Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Giordano","sequence":"additional","affiliation":[{"name":"Department of Medical and Surgical Sciences,\u00a0Division of Cardiology \"Magna Graecia\" University Catanzaro Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6103-8510","authenticated-orcid":false,"given":"Giuseppe","family":"Biondi\u2010Zoccai","sequence":"additional","affiliation":[{"name":"Department of Medical\u2010Surgical Sciences and Biotechnologies Sapienza University of Rome Latina Italy"},{"name":"Mediterranea Cardiocentro Napoli Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5116-2737","authenticated-orcid":false,"given":"Stefano","family":"Rigattieri","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit,\u00a0Sant'Andrea University Hospital Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca","family":"Giovannelli","sequence":"additional","affiliation":[{"name":"Interventional Cardiology Unit,\u00a0Sant'Andrea University Hospital Rome Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arturo","family":"Giordano","sequence":"additional","affiliation":[{"name":"Unit\u00e0 Operativa di Interventistica Cardiovascolare, Pineta Grande Hospital Castel Volturno Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,5,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.23736\/S2724-5683.21.05538-9"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","unstructured":"TerrosuP BoccanelliA SabinoG et al.Severe aortic stenosis and transcatheter aortic valve replacement in elderly patients: utility vs futility.Minerva Med. 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