{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T21:23:56Z","timestamp":1783200236120,"version":"3.54.6"},"reference-count":26,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T00:00:00Z","timestamp":1649376000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","award":["CDA 15\u2010072"],"award-info":[{"award-number":["CDA 15\u2010072"]}],"id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify trends in transcatheter aortic valve replacement (TAVR) use and outcomes by race (non\u2010Hispanic White, Black), ethnicity (Hispanic), and sex over time.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Despite rapid growth in TAVR use over time, our understanding of its use and outcomes among males and females of underrepresented racial\/ethnic groups remains limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective analysis of hospitalizations from 2013 to 2017 from the Healthcare Cost and Utilization Project database was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>White patients comprised 65% (<jats:italic>n<\/jats:italic>\u2009=\u20092.16\u2009\u00d7\u200910<jats:sup>7<\/jats:sup>) of all hospitalizations, yet they comprised 83% (<jats:italic>n<\/jats:italic>\u2009=\u2009176,887) of the admissions for aortic stenosis (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001). Among 91,693 hospitalizations for aortic valve replacement, 64,069 were surgical (34.0% female, 7.0% Hispanic, and 5.9% Black) and 27,624 were transcatheter (46.6% female, 4.5% Hispanic, and 4.4% Black). Growth in TAVR volumes was the slowest among minorities and females. Hispanic males, Hispanic females, and White females had the highest in\u2010hospital mortality (2.7%\u20133.3%; compared to White males, adjusted odds ratio: Hispanic males 1.9 [1.2\u20133.0], Hispanic females 1.9 [1.2\u20133.1], and White females 1.4 [1.2\u20131.7]). Despite less baseline\u00a0vascular disease, females of all races\/ethnicities had more vascular complications than men (female 5% vs. male 3.5%, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001). Further adjustment for vascular complications only partially attenuated mortality differences. Black and Hispanic patients had a longer mean length of hospital stay than White patients, which was most pronounced among females. Pacemaker requirements were consistently low among all groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Differences in TAVR growth and outcomes by race, ethnicity, and sex over time highlight areas for focused efforts to close gaps in minimally invasive structural heart disease care.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30182","type":"journal-article","created":{"date-parts":[[2022,4,8]],"date-time":"2022-04-08T20:43:44Z","timestamp":1649450624000},"page":"2092-2100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Temporal trends in transcatheter aortic valve replacement use and outcomes by race, ethnicity, and sex"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3054-6576","authenticated-orcid":false,"given":"Celina M.","family":"Yong","sequence":"first","affiliation":[{"name":"Division of Cardiology Veterans Affairs Palo Alto Healthcare System  Palo Alto California USA"},{"name":"Division of Cardiovascular Medicine, Stanford Cardiovascular Institute Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina","family":"Jaluba","sequence":"additional","affiliation":[{"name":"Department of Medicine Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Batchelor","sequence":"additional","affiliation":[{"name":"Division of Cardiology Inova Heart and Vascular Institute  Falls Church Virginia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Gummipundi","sequence":"additional","affiliation":[{"name":"Division of Cardiology Veterans Affairs Palo Alto Healthcare System  Palo Alto California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M.","family":"Asch","sequence":"additional","affiliation":[{"name":"Division of Cardiology Veterans Affairs Palo Alto Healthcare System  Palo Alto California USA"},{"name":"Department of Medicine Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Heidenreich","sequence":"additional","affiliation":[{"name":"Division of Cardiology Veterans Affairs Palo Alto Healthcare System  Palo Alto California USA"},{"name":"Division of Cardiovascular Medicine, Stanford Cardiovascular Institute Stanford University School of Medicine  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,4,8]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1901109"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.08.1035"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.08.056"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.041"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400590"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.02.537"},{"key":"e_1_2_10_9_1","unstructured":"NIS Database Documentation [Internet]. 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