{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T00:35:45Z","timestamp":1781742945399,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T00:00:00Z","timestamp":1656288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To examine the rate of readmission for permanent pacemaker (PPM) implantation with early versus late discharge after transcatheter aortic valve replacement (TAVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>There is a current trend toward\u00a0early discharge after TAVR. However, paucity of data exists on the impact of such practice on readmissions for PPM implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Nationwide Readmission Database 2016\u20132018 was queried for all hospitalizations where patients underwent TAVR. Hospitalizations were stratified into early (Days 0 and 1) versus late (\u2265Day 2) discharge groups. Observations in which PPM was required in the index admission were excluded. Multivariable regression analyses involving patient\u2010 and hospital\u2010related variables were utilized. The primary outcome was 90\u2010day readmission for PPM implantation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The final analysis included 68,482 TAVR hospitalizations, 20,261 (29.6%) with early versus 48,221 (70.4%) with late discharge. Early discharge after TAVR increased over the study period (16.2% in 2016 vs. 37.9% in 2018, <jats:italic>P<\/jats:italic><jats:sub>trend<\/jats:sub>\u2009&lt;\u20090.01). Nevertheless, 90\u2010day readmission for PPM implantation remained stable (1.8% in 2016 vs. 2.0% in 2018, <jats:italic>P<\/jats:italic><jats:sub>trend<\/jats:sub>\u2009=\u20090.32). The 90\u2010day readmission rate for PPM implantation (2.0% vs. 1.8%; adjusted odds ratio: 1.15; 95% confidence interval: 0.95\u20131.39; <jats:italic>p<\/jats:italic>\u2009=\u20090.15) and median time\u2010to\u2010readmission (5 days [interquartile range,\u00a0IQR 3\u20139] vs. 5 days [IQR 3\u201314], <jats:italic>p<\/jats:italic>\u2009=\u20090.92) were similar with early versus late discharge. Similar rates were observed regardless of whether readmission was elective versus not. Early discharge was associated with lower hospitalization cost ($39,990\u2009\u00b1\u2009$13,681 vs. $46,750\u2009\u00b1\u2009$18,218, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01) compared with late discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In patients who did not require PPM during the index TAVR hospitalization, the rate of readmission for PPM implantation was similar with early versus late discharge.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30299","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T10:39:42Z","timestamp":1656326382000},"page":"245-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Early versus late discharge after transcatheter aortic valve replacement and readmissions for permanent pacemaker implantation"],"prefix":"10.1002","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9926-8423","authenticated-orcid":false,"given":"Ahmed M.","family":"Elzanaty","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine University of Toledo  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Maraey","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of North Dakota  Bismarck North Dakota USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4248-781X","authenticated-orcid":false,"given":"Ayman","family":"Elbadawi","sequence":"additional","affiliation":[{"name":"Section of Cardiology, Baylor College of Medicine  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0922-9672","authenticated-orcid":false,"given":"Mahmoud","family":"Khalil","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Lincoln Medical Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Hashim","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Ain Shams University  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9962-861X","authenticated-orcid":false,"given":"Rohit","family":"Vyas","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Toledo  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelmoneim","family":"Moustafa","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine University of Toledo  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Periakaruppan Kasi","family":"Ramanthan","sequence":"additional","affiliation":[{"name":"Heart and Vascular institute, Promedica Toledo Hospital  Toledo Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amgad","family":"Mentias","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2560-0155","authenticated-orcid":false,"given":"J. Dawn","family":"Abbott","sequence":"additional","affiliation":[{"name":"Department of Medicine,\u00a0Division of Cardiology Alpert Medical School of Brown University  Providence Rhode Island USA"},{"name":"Lifespan Cardiovascular Institute  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert D.","family":"Aronow","sequence":"additional","affiliation":[{"name":"Department of Medicine,\u00a0Division of Cardiology Alpert Medical School of Brown University  Providence Rhode Island USA"},{"name":"Lifespan Cardiovascular Institute  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0026-3391","authenticated-orcid":false,"given":"Samir","family":"Kapadia","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Heart and Vascular Institute, Cleveland Clinic Foundation  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2280-8030","authenticated-orcid":false,"given":"Marwan","family":"Saad","sequence":"additional","affiliation":[{"name":"Department of Medicine,\u00a0Division of Cardiology Alpert Medical School of Brown University  Providence Rhode Island USA"},{"name":"Lifespan Cardiovascular Institute  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,27]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"e201632","article-title":"The development of transcatheter aortic valve replacement (TAVR)","volume":"2016","author":"Cribier A","year":"2016","journal-title":"Glob Cardiol Sci Pract"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.06.076"},{"issue":"5","key":"e_1_2_8_4_1","first-page":"e72","article-title":"2020 ACC\/AHA Guideline for the Management of Patients With Valvular Heart Disease: a Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"143","author":"Otto CM","year":"2021","journal-title":"Circulation"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.05.010"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.15420\/AER.2015.04.02.81"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.033"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-158-1-201301010-00007"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2016.07.026"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28156"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.09.034"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.07.747"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028352"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.02.068"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2021.11.020"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.08.050"},{"issue":"2","key":"e_1_2_8_17_1","first-page":"182","article-title":"Safety and feasibility of same day discharge after transcatheter aortic valve replacement post COVID\u201019. structural","volume":"5","author":"Russo MJ","year":"2021","journal-title":"Heart"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29453"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.12.020"},{"key":"e_1_2_8_20_1","unstructured":"CostH ProjectU. 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