{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T09:47:34Z","timestamp":1747302454882,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>There are limited data on outcomes of PCI in surgical turndown patientsespecially in those presenting with ACS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>A retrospective analysis of prospectively collected data of patients who were turned down for CABG and had PCI between 2013 and 2020. All consecutive patients (449), ACS (<jats:italic>n<\/jats:italic>\u2009=\u2009245) and no\u2010ACS\u00a0(<jats:italic>n<\/jats:italic>\u2009=\u2009204) were included. In\u2010hospital complications occurred in 28 patients (6.2%). At 30 days, 27 patients (6.0%) died (18 patients in the ACS group [7.3%] vs. 9 patients in the no\u2010ACS group [4.4%], <jats:italic>p<\/jats:italic>\u2009=\u20090.23). Following multivariate analysis, no significant difference in long\u2010term mortality was observed between the two groups (median follow\u2010up of 4 [2\u20136] years, hazard ratio [HR]: 1.08, 95% confidence interval [CI]: 0.75\u20131.58, <jats:italic>p<\/jats:italic>\u2009=\u20090.667). In propensity score\u2010matched analysis, the adjusted mortality risk was also not different between the groups (HR: 0.74, 95% CI: 0.25\u20131.26, <jats:italic>p<\/jats:italic>\u2009=\u20090.374). Independent predictors of mortality included chronic kidney disease stage\u2009\u2265\u20093 (HR:\u00a01.64, 95% CI: 1.13\u20132.39, <jats:italic>p<\/jats:italic>\u2009=\u20090.009), high European System for Cardiac Operative Risk Evaluation II\u00a0(HR:\u00a01.02, 95% CI: 1.00\u20131.05, <jats:italic>p<\/jats:italic>\u2009=\u20090.035), and laser atherectomy use (HR:\u00a03.35, 95% CI: 1.32\u20138.54, <jats:italic>p<\/jats:italic>\u2009=\u20090.011).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PCI in surgical patients turndown patients appears safe. ACSpresentation was associated with more comorbid illnesses; however, afteradjustment, ACS did not independently confer additional risk of mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30318","type":"journal-article","created":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T12:32:45Z","timestamp":1656678765000},"page":"360-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Clinical outcomes of percutaneous coronary intervention in high\u2010risk patients turned down for surgical revascularization"],"prefix":"10.1002","volume":"100","author":[{"given":"Mohamed","family":"Farag","sequence":"first","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle upon Tyne UK"},{"name":"Department of Clinical, Pharmaceutical and Biological Science University of Hertfordshire Hertfordshire 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