{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:47:35Z","timestamp":1761864455097,"version":"3.37.3"},"reference-count":34,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T00:00:00Z","timestamp":1661817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The aim of this study was to investigate the degree of functional improvement of a transcatheter heart valve (THV) for valve\u2010in\u2010valve after bioprosthetic valve fracture (BVF) of three small surgical aortic valve bioprostheses (SAVBP) using high\u2010pressure balloon aortic valvuloplasty (HP\u2010BAV) under standardized ex\u2010vivo\u2010conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A THV 26\u2009mm (Evolut R) and SAVBP 21\u2009mm (Perimount Magna Ease, Trifecta, and Epic supra [<jats:italic>n<\/jats:italic>\u2009=\u20094] were used. Mean pressure gradient (MPG), effective orifice area (EOA), geometric orifice area (GOA), minimal internal diameter (MID), and pinwheeling index (PWI) were analyzed before and after HP\u2010BAV of the SAVBP using a noncompliant balloon. Fracturing of the SAVBP was done before implantation of the THV and the balloon pressures at the point of fracture were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The Magna Ease and Epic fractured at balloon pressures of 18 and 8\u2009atm, respectively. The Trifecta did not fracture up to a balloon pressure of 30\u2009atm but was dilated. HP\u2010BAV led to increased THV expansion as evident by straightened coaptation lines of the Evolut R 26\u2009mm with reduced PWI, increased MID, and increased GOA in all 21\u2009mm SAVBP. Evolut R showed significantly lower MPG and higher EOA as ViV in all prostheses after HP\u2010BAV (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). MPG and EOA of Evolut R differed regarding the SAVBP. Evolut R presented the lowest MPG and highest EOA in Magna Ease and the highest MPG and lowest EOA in Epic supra.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The degree of function improvement of the same THV as ViV after HP\u2010BAV depends on the surgical valve model. Functional improvement can also be achieved without valve fracture.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30359","type":"journal-article","created":{"date-parts":[[2022,8,30]],"date-time":"2022-08-30T15:42:09Z","timestamp":1661874129000},"page":"841-849","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Impact of high\u2010pressure balloon aortic valvuloplasty on the hydrodynamic result after a transcatheter valve\u2010in\u2010valve procedure"],"prefix":"10.1002","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2715-1760","authenticated-orcid":false,"given":"Najla","family":"Sadat","sequence":"first","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Bruhn","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Scharfschwerdt","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tim","family":"Schaller","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anas","family":"Aboud","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Saisho","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ingo","family":"Eitel","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Cardiology, Angiology and Intensive Care, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Ensminger","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Buntaro","family":"Fujita","sequence":"additional","affiliation":[{"name":"Department of Cardiac and Thoracic Vascular Surgery, University Medical Center Schleswig\u2010Holstein Campus L\u00fcbeck L\u00fcbeck Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,8,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.21300"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2013.10.001"},{"key":"e_1_2_10_4_1","doi-asserted-by":"crossref","unstructured":"SadatN BruhnD ScharfschwerdtM et al.Impact of different valve\u2010in\u2010valve positions on the hydrodynamic performance of the newest\u2010generation self\u2010expanding transcatheter heart valve.Eur J Cardiothorac Surg. 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