{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T12:33:03Z","timestamp":1764333183746,"version":"3.37.3"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T00:00:00Z","timestamp":1663459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Patients with rapidly deteriorating clinical status due to severe aortic stenosis are often referred for expedited transcatheter aortic valve replacement (TAVR). Data regarding the outcome of such interventions is limited. We aimed to evaluate the outcome of patients undergoing expedited TAVR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design and Setting<\/jats:title><jats:p>Data were derived from the Israeli Multicenter Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Subjects<\/jats:title><jats:p>Subjects were divided into two groups based on procedure urgency: patients who were electively hospitalized for the procedure (<jats:italic>N<\/jats:italic>\u2009=\u20093140) and those who had an expedited TAVR (<jats:italic>N<\/jats:italic>\u2009=\u2009142). Procedural and periprocedural complication rates were significantly higher among patients with an expedited indication for TAVR compared to those having an elective procedure: valve malposition 4.6% versus 0.6% (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), procedural cardiopulmonary resuscitation 4.3% versus 1.0% (<jats:italic>p<\/jats:italic>\u2009=\u20090.007), postprocedure myocardial infarction 2.0% versus 0.4% (<jats:italic>p<\/jats:italic>\u2009=\u20090.002), and stage 3 acute kidney injury 3.0% versus 1.1%, (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Patients with expedited indication for TAVR had significantly higher in hospital mortality (5.6% vs. 1.4%, <jats:italic>p<\/jats:italic>\u2009=\u20090.003). Kaplan\u2013Meier's survival analysis showed that patients undergoing expedited TAVR had higher 3\u2010year mortality rates compared to patients undergoing an elective TAVR procedure (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Multivariate analysis found that patients with expedited indication had fourfolds increased risk of in\u2010hospital mortality (odds ratio: 4.07, <jats:italic>p<\/jats:italic>\u2009=\u20090.001), and nearly twofolds increased risk of mortality at 3\u2010year (hazard ratio: 1.69, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) compared to those having an elective procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Patients with expedited indications for TAVR suffer from poor short\u2010 and long\u2010term outcomes. It is important to characterize and identify these patients before the deterioration to perform TAVR in a fast\u2010track pathway to minimize their procedural risk.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30386","type":"journal-article","created":{"date-parts":[[2022,9,18]],"date-time":"2022-09-18T09:54:02Z","timestamp":1663494842000},"page":"832-838","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Procedural and long\u2010term outcome among patients undergoing expedited trans\u2010catheter aortic valve replacement"],"prefix":"10.1002","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4589-5296","authenticated-orcid":false,"given":"Anat","family":"Berkovitch","sequence":"first","affiliation":[{"name":"Division of Cardiology, Leviev Heart and Vascular Center Chaim Sheba Medical Center  Tel Hashomer Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv 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Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7708-8253","authenticated-orcid":false,"given":"Ran","family":"Kornowski","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of Cardiology Rabin Medical Center  Petach\u2010Tikva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haim","family":"Danenberg","sequence":"additional","affiliation":[{"name":"The Heart Institute, Hadassah Ein\u2010Karem Medical Center The Hebrew University  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Fefer","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Leviev Heart and Vascular Center Chaim Sheba Medical Center  Tel Hashomer Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana Vaknin","family":"Assa","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of Cardiology Rabin Medical Center  Petach\u2010Tikva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9398-471X","authenticated-orcid":false,"given":"Maayan","family":"Konigstein","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of Cardiology Tel Aviv Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3294-5968","authenticated-orcid":false,"given":"Ilan","family":"Merdler","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of Cardiology Tel Aviv Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gidon","family":"Perlman","sequence":"additional","affiliation":[{"name":"The Heart Institute, Hadassah Ein\u2010Karem Medical Center The Hebrew University  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elad","family":"Maor","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Leviev Heart and Vascular Center Chaim Sheba Medical Center  Tel Hashomer Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rivka","family":"Carmiel","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Leviev Heart and Vascular Center Chaim Sheba Medical Center  Tel Hashomer Israel"},{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Planer","sequence":"additional","affiliation":[{"name":"The Heart Institute, Hadassah Ein\u2010Karem Medical Center The Hebrew University  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ariel","family":"Banai","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of Cardiology Tel Aviv Medical Center  Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mony","family":"Shuvy","sequence":"additional","affiliation":[{"name":"The Heart Institute, Hadassah Ein\u2010Karem Medical Center The Hebrew University  Jerusalem Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abid R.","family":"Assali","sequence":"additional","affiliation":[{"name":"Sackler School of Medicine Tel\u2010Aviv University  Tel Aviv Israel"},{"name":"Division of 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