{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T14:20:24Z","timestamp":1784384424716,"version":"3.55.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T00:00:00Z","timestamp":1670371200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>We aimed to evaluate the feasibility and safety of carotid artery stenting (CAS) with a newly designed double\u2010layer micromesh stent using wrist approach in patients with significant carotid disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Between January 2016 and December 2021, 105 patients undergoing CAS\u00a0with Roadsaver\u2122 stent were enrolled in a single center prospective study. Follow\u2010up assessments included neurological exams, duplex ultrasound (DUS), and 12\u2010lead ECG. The primary endpoint was the 30\u2010day composite rate of stroke, death, and myocardial infarction. Secondary endpoints included procedure success, access site complications, device success, target lesion revascularization, and in\u2010stent restenosis evaluated with DUS. Long\u2010term outcomes up to 72 months of follow\u2010up were assessed in all eligible patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The study population was predominantly male (69.5%) with a median age of 68\u2009\u00b1\u20098 years. Patients were symptomatic in 80% of the cases, and 35% fulfilled the high\u2010risk criteria for surgical endarterectomy. The right internal carotid artery was the target artery in 56 (53.4%), and the left in 49 (46.6%) of the cases. All procedures were successfully completed from the right wrist, with right radial access in 94 (89.5%) cases and ulnar artery access with previous radial artery occlusion in 11 (10.5%) cases. All patients were treated successfully with the study device. The primary endpoint was met with a 30\u2010day major adverse event\u00a0rate of 0.9% (1\/105). Up to 72 months of follow\u2010up (median 30\u2009\u00b1\u200920 months) there were no strokes, neurological deaths, or target lesion revascularization of the treated lesion. Doppler ultrasound examination revealed nonsignificant in\u2010stent restenosis in two asymptomatic patients. There was no hand ischemia detected in any patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Results from this study demonstrate the radial and ulnar access for CAS\u00a0with double layer micromesh Roadsaver\u2122 stent is safe and feasible and associated with favorable early and long\u2010term follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30514","type":"journal-article","created":{"date-parts":[[2022,12,7]],"date-time":"2022-12-07T16:50:10Z","timestamp":1670431810000},"page":"154-163","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Radial and ulnar approach for carotid artery stenting with Roadsaver\u2122 double layer micromesh stent:\u00a0Early and long\u2010term follow\u2010up"],"prefix":"10.1002","volume":"101","author":[{"given":"Danica","family":"Petkoska","sequence":"first","affiliation":[{"name":"University Clinic of Cardiology Skopje North 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