{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:10:45Z","timestamp":1740103845330,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T00:00:00Z","timestamp":1673654400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>One limitation to transradial access (TRA) is the occurrence of spasms (RAS), for which the use of prophylactic medications is recommended. Improvement in TRA material combined with the increase in operators' expertise, might mitigate this benefit. We assess the effect of preventive nitroglycerin on RAS during TRA, evaluating the role of the operator's experience. Patients received 500\u2009\u03bcg nitroglycerin or placebo. The operator's expertise was classified as: inexperienced (I), intermediate (M), and experienced (E). 2040 patients were included. Prophylactic use of nitroglycerin did not reduce RAS (10.8% vs. 13.4% (placebo), <jats:italic>p<\/jats:italic>\u2009=\u20090.07). RAS incidence was 14.5% in I, 12.5% in M, and 9.7% in E (<jats:italic>p<\/jats:italic>\u2009=\u20090.01). In group I, nitroglycerin reduced RAS (17.4% vs. 11.1%, <jats:italic>p<\/jats:italic>\u2009=\u20090.04), which was not observed in other groups. Overall, nitroglycerin does not prevent RAS, which is more common among inexperienced operators. More experienced operators could abolish preventive nitroglycerin use.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30541","type":"journal-article","created":{"date-parts":[[2023,1,14]],"date-time":"2023-01-14T19:09:30Z","timestamp":1673723370000},"page":"579-586","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effect of randomized prophylactic nitroglycerin on radial artery spasm during transradial catheterization: An analysis based on operator experience"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7847-4009","authenticated-orcid":false,"given":"Roberto L.","family":"da Silva","sequence":"first","affiliation":[{"name":"Department of Interventional Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"},{"name":"Department of Interventional Cardiology Instituto de Cardiologia de Santa Catarina  S\u00e3o Jos\u00e9 Santa Catarina Brazil"},{"name":"Department of Cardiology Hospital Universit\u00e1rio Prof. Polydoro Ernani de S\u00e3o Thiago Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7502-8049","authenticated-orcid":false,"given":"George D.","family":"Dangas","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Mount Sinai Medical Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3511-7375","authenticated-orcid":false,"given":"Pedro B","family":"de Andrade","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Santa Casa de Mar\u00edlia  Mar\u00edlia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo M.","family":"Joaquim","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto de Cardiologia de Santa Catarina  S\u00e3o Jos\u00e9 Santa Catarina Brazil"},{"name":"Department of Cardiology Hospital Universit\u00e1rio Prof. Polydoro Ernani de S\u00e3o Thiago Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thais R. W.","family":"da Silva","sequence":"additional","affiliation":[{"name":"Department of Cardiology Hospital Universit\u00e1rio Prof. Polydoro Ernani de S\u00e3o Thiago Florian\u00f3polis Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tammuz","family":"Fattah","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto de Cardiologia de Santa Catarina  S\u00e3o Jos\u00e9 Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanderlei C.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto de Cardiologia de Santa Catarina  S\u00e3o Jos\u00e9 Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo A.","family":"Zanella","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto de Cardiologia de Santa Catarina  S\u00e3o Jos\u00e9 Santa Catarina Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda G. M.","family":"Sousa","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fausto","family":"Feres","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6286-3109","authenticated-orcid":false,"given":"Jos\u00e9 R.","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Instituto Dante Pazzanese de Cardiologia S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,1,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27989"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2012.01.015"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25082"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20812"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2015.08.008"},{"key":"e_1_2_10_7_1","first-page":"461","article-title":"Different spasmolytic regimens (nitroglycerin vs verapamil) and the incidence of radial artery occlusion after transradial catheterization","volume":"30","author":"Dharma S","year":"2018","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.02.026"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1307"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.11.005"},{"key":"e_1_2_10_11_1","first-page":"100","article-title":"A study comparing transradial catheterisation with or without prophylactic nitroglycerin","volume":"24","author":"Silva RL","year":"2017","journal-title":"Br J Cardiol"},{"key":"e_1_2_10_12_1","first-page":"527","article-title":"Radial artery spasm during transradial coronary procedures","volume":"23","author":"Kristi\u0107 I","year":"2011","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.006356"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.638627"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/hc1002.105186"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000588"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30541","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.30541","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30541","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T18:56:46Z","timestamp":1692730606000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,14]]},"references-count":15,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["10.1002\/ccd.30541"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30541","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2023,1,14]]},"assertion":[{"value":"2022-08-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-12-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}