{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:19:06Z","timestamp":1785449946073,"version":"3.56.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T00:00:00Z","timestamp":1674691200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We review our experience with 13 periprocedural aortic dissection (AD) cases caused by transcatheter aortic valve replacement\u00a0(TAVR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>AD is a potentially lethal complication of TAVR; however, only sporadic case reports have been published to date.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Among 1335 consecutive patients who underwent TAVR in 2013\u20132021, we retrospectively extracted 13 patients (1.0%) with TAVR\u2010related AD (Stanford type A in 6 [46%], type B in 7 [54%]). AD was defined as a new\u2010onset dissected layer of the aortic wall and diagnosed by aortography, computed tomography, or transesophageal echocardiography.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Five of the six type A AD cases (83%) were detected during TAVR versus only one of the seven type B AD cases (14%). Four of the seven type B AD cases (57%) were asymptomatic and incidentally detected on computed tomography. The presumed causes of AD were injury by the delivery sheath (39%), delivery catheter (23%), valve implantation (15%), stent edge (15%), and pre\u2010dilation balloon (8%). Complicated AD occurred in only one patient (8%). Considering the patient's age and prohibitive surgical risk, all patients were treated conservatively and free of any aortic\u2010related deaths or interventions during a follow\u2010up of 1087 days.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>TAVR\u2010related AD is a rare but life\u2010threatening condition that may be underdiagnosed. Its optimal therapy remains unclear, and conservative management might be an option for selected patients. Further studies are needed to elucidate the incidence, risk factors, effective screening, optimal therapy, and outcomes of TAVR\u2010related AD.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30574","type":"journal-article","created":{"date-parts":[[2023,1,26]],"date-time":"2023-01-26T18:44:30Z","timestamp":1674758670000},"page":"668-675","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Transcatheter aortic valve replacement\u2010related aortic dissection: A clinical case series"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4873-9029","authenticated-orcid":false,"given":"Takashi","family":"Hiruma","sequence":"first","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Higuchi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Saji","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itaru","family":"Takamisawa","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Shimokawa","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoru","family":"Nanasato","sequence":"additional","affiliation":[{"name":"Department of Cardiology Sakakibara Heart Institute Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000047200.36165.B8"},{"key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1016\/j.jacc.2020.09.595","article-title":"STS\u2010ACC TVT registry of transcatheter aortic valve replacement","volume":"76","author":"Carroll JD","year":"2020","journal-title":"JACC: Cardiovasc\u00a0Interv"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab773"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.10.021"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.25997"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-015-0324-6"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-018-1183-8"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu281"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.jacc.2010.12.005","article-title":"Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials","volume":"57","author":"Leon MB","year":"2011","journal-title":"JACC: Cardiovasc\u00a0Interv"},{"key":"e_1_2_9_11_1","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1016\/j.jacc.2015.03.034","article-title":"Perioperative results and complications in 15,964 transcatheter aortic valve replacements","volume":"65","author":"Walther T","year":"2015","journal-title":"JACC: Cardiovasc\u00a0Interv"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.907402"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2021.08.009"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.22900"},{"key":"e_1_2_9_15_1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.jacc.2015.05.029","article-title":"Presentation, diagnosis, and outcomes of acute aortic dissection","volume":"66","author":"Pape LA","year":"2015","journal-title":"JACC: Cardiovasc\u00a0Interv"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.843615"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2016.07.078"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2012.06.032"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.09.079"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.11.077"},{"key":"e_1_2_9_21_1","unstructured":"JCS\/JSCS\/JATS\/JSVS 2020 Guideline on Diagnosis and Treatment of Aortic Aneurysm and Aortic Dissection. 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