{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:32:43Z","timestamp":1778110363353,"version":"3.51.4"},"reference-count":19,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T00:00:00Z","timestamp":1681084800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Obesity has been associated with an increased risk of vascular complication during percutaneous coronary intervention, but there are no data on the risk of vascular complication during percutaneous transfemoral transcatheter aortic valve insertion (TAVI).<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We hypothesized there would be a similar increased risk associated with TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We reviewed the records of 1176 patients who received percutaneous transfemoral transcatheter aortic valve insertion from September 2015 to September 2020. All patients received 1) preoperative computed tomoraphy angiography assessment of the abdomen and pelvis to delineate iliofemoral artery anatomy, 2) ultrasound\u2010guided percutaneous femoral arterial access, and 3) pre\u2010closure of the delivery sheath femoral access site. Vascular complication was recorded based on definitions set forth by Valve Academic Research Consortium 3.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The median age of patients was 81 years, and 60% were men. The median body mass index (BMI) was 29\u2009kg\/m<jats:sup>2<\/jats:sup> (range, 11\u201367), and 91 (8%) patients had a value \u226540\u2009kg\/m<jats:sup>2<\/jats:sup> (i.e., morbid obesity). Delivery sheath size was 14\u2010French in 859 (73%) patients, 16\u2010French in 311 (26%), and 18\u2010French in 6 (1%). Vascular complication occurred in 53 (5%) patients, including 39 (7%) among the first half of procedures and 14 (2%) among the second half (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). When stratified by obesity status (BMI\u2009&lt;\u2009or \u226530\u2009kg\/m<jats:sup>2<\/jats:sup>, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), the complication rate was 4% in nonobese patients and 5% in obese patients. Multivariable analysis showed no overall association between risk of vascular complication and BMI categories (<jats:italic>p<\/jats:italic>\u2009=\u20090.583)BMI continuous values (<jats:italic>p<\/jats:italic>\u2009=\u20090.529), or sheath size (<jats:italic>p<\/jats:italic>\u2009=\u20090.217).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Obesity is not associated with a vascular complication during percutaneous transfemoral transcatheter aortic valve insertion. The operation should not be denied in obese patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30658","type":"journal-article","created":{"date-parts":[[2023,4,10]],"date-time":"2023-04-10T13:20:41Z","timestamp":1681132841000},"page":"1221-1228","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Obesity and vascular complication in percutaneous transfemoral transcatheter aortic valve insertion"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9729-3134","authenticated-orcid":false,"given":"Motahar","family":"Hosseini","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian D.","family":"Lahr","sequence":"additional","affiliation":[{"name":"Department of Biomedical Statistics and Informatics Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin L.","family":"Greason","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arman","family":"Arghami","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajiv","family":"Gulati","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6082-5379","authenticated-orcid":false,"given":"Mackram F.","family":"Eleid","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan A.","family":"Crestanello","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Mayo Clinic Rochester Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,4,10]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816885"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.09.595"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.11.033"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1514616"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.01.065"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2004.07.088"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.120.019051"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.02.038"},{"key":"e_1_2_9_11_1","unstructured":"Edwards Lifesciences Corporation.2018 Instructions for Use for Edwards Lifesciences Products. 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