{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:16:42Z","timestamp":1792192602095,"version":"4.4.0"},"reference-count":39,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T00:00:00Z","timestamp":1681776000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) is associated with higher risk of mortality and rehospitalization for heart failure. Efforts to prevent conduction abnormalities (CA) requiring PPI after TAVI should be made. The membranous septum (MS) length and its interaction with implantation depth (ID\u2013\u0394MSID) could provide useful information about the risk of CA\/PPI following TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To identify MS length and \u0394MSID as predictors of CA\/PPI following TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Study\u2010level meta\u2010analysis of studies published by September 30, 2022.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighteen studies met our eligibility including 5740 patients. Shorter MS length was associated with a significantly higher risk of CA\/PPI (per 1\u2009mm decrease: odds ratio [OR] 1.60, 95% confidence interval [CI] 1.28\u20131.99, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Similarly, lower \u0394MSID was associated with a significantly higher risk of CA\/PPI (per 1\u2009mm decrease: OR 1.75, 95%\u00a0CI 1.32\u20132.31, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Meta\u2010regression analyses revealed a statistically significant modulation of the effect of shorter MS length and lower \u0394MSID on the outcome (CA\/PPI) by balloon postdilatation (positive regression coefficients with <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001); with increasing use of balloon postdilatation, the effect of shorter MS length and lower \u0394MSID on the outcome increased. MS length and \u0394MSID demonstrated excellent discriminative abilities, with diagnostic ORs equaling 9.49 (95%\u00a0CI 4.73\u201319.06), and 7.19 (95%\u00a0CI 3.31\u201315.60), respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Considering that short MS length and low \u0394MSID are associated with higher risk of CA and PPI, we should include measurement of MS length in the pre\u2010TAVI planning with MDCT and try to establish optimal ID values before the procedure to avoid CA\/PPI.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30666","type":"journal-article","created":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T09:13:11Z","timestamp":1681809191000},"page":"1203-1213","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Computed tomography\u2010derived membranous septum length as predictor of conduction abnormalities and permanent pacemaker implantation after TAVI: A meta\u2010analysis of observational studies"],"prefix":"10.1002","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5356-2996","authenticated-orcid":false,"given":"Michel Pompeu","family":"S\u00e1","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"},{"name":"Department of Cardiothoracic Surgery Research Lankenau Institute for Medical Research Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jef","family":"Van den Eynde","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xander","family":"Jacquemyn","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Sciences KU Leuven Leuven Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozgun","family":"Erten","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Research Lankenau Institute for Medical Research Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Goldman","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Coady","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Gnall","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4676-2839","authenticated-orcid":false,"given":"William A.","family":"Gray","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harish","family":"Jarrett","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Imaging Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra V.","family":"Abramson","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Imaging Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie\u2010Annick","family":"Clavel","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Department of Medicine, Faculty of Medicine Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Pibarot","sequence":"additional","affiliation":[{"name":"Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Qu\u00e9bec Qu\u00e9bec City Qu\u00e9bec Canada"},{"name":"Department of Medicine, Faculty of Medicine Universit\u00e9 Laval Qu\u00e9bec City Qu\u00e9bec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basel","family":"Ramlawi","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Lankenau Medical Center,\u00a0Lankenau Heart Institute, Main Line Health Wynnewood Pennsylvania USA"},{"name":"Department of Cardiothoracic Surgery Research Lankenau Institute for Medical Research Wynnewood Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscai.2022.100434"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14986"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ30V6I4A80"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2016.11.020"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.10.016"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.05.056"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_10_9_1","unstructured":"ROBINS\u2010E Development Group. Risk Of Bias in Nonrandomized Studies of Exposure (ROBINS\u2010E) 1 June Launch version 1 June 2022.2022.https:\/\/www.riskofbias.info\/welcome\/robins-e-tool"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.7588"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2307\/2533446"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/0272989X08319957"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/sim.942"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-21-00363"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-022-02576-y"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/openhrt-2022-001995"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carrev.2022.03.018"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.07.072"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-021-02365-2"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-021-01999-5"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30377"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2022.07.003"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.757190"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2020.10.002"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.120.009028"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2020.01.008"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.33963\/KP.15538"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-20-0257"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-19-0823"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.03.014"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30073-3"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1700456"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.28957"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehp537"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29805"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.05.010"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30562"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2018.12.003"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30666","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T10:53:55Z","timestamp":1692528835000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,18]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1002\/ccd.30666"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30666","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,18]]},"assertion":[{"value":"2023-01-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-08","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}