{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T20:31:00Z","timestamp":1784925060364,"version":"3.55.0"},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T00:00:00Z","timestamp":1689811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Coronary artery disease (CAD)\u00a0is a common finding in patients undergoing transcatheter aortic valve implantation (TAVI).\u00a0However, its prognostic significance and its management remains controversial.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This study sought to determine whether the presence of CAD, its complexity, and angiography\u2010guided percutaneous coronary intervention (PCI) are associated with outcomes after TAVI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>All patients undergoing TAVI at a tertiary referral center between 2008 and 2018 were included in a prospective observational study. Baseline SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) score (SS)\u00a0and a residual SS after PCI were calculated. The endpoints on the 5 year follow\u2010up were all\u2010cause mortality and a composite of mayor cardiovascular adverse events (MACE).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 379 patients, the presence of CAD and its complexity were not significantly associated with worse 5\u2010year survival after TAVI, with a mortality for SS0 of 45%; for SS 1\u201322 of 36.5% (HR\u00a00.77; 95% CI 0.53\u20131.11, <jats:italic>p<\/jats:italic>\u2009=\u20090.15) and for SS\u2009&gt;\u200922 of 42.1% (HR 1.24; 95% CI 0.59\u20132.63, <jats:italic>p<\/jats:italic>\u2009=\u20090.57). Regarding the combined event of MACE, there were also no statistically significant differences between patients with CAD and without CAD (56.8% in patients without CAD and 54.9% in patients with CAD; HR 1.06; 95% CI 0.79\u20131.43, <jats:italic>p<\/jats:italic>\u2009=\u20090.7). Angiography\u2010guided PCI or completeness of revascularization was not associated with different outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the present analysis, neither the presence nor the extent of CAD, nor the degree of revascularization, was associated with a prognostic impact in patients undergoing TAVI at 5\u2010year follow\u2010up.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30767","type":"journal-article","created":{"date-parts":[[2023,7,20]],"date-time":"2023-07-20T20:58:45Z","timestamp":1689886725000},"page":"513-520","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Prognostic impact of coronary lesions and its revascularization in a 5\u2010year follow\u2010up after the TAVI procedure"],"prefix":"10.1002","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2704-7218","authenticated-orcid":false,"given":"Domingo Jos\u00e9 L\u00f3pez","family":"V\u00e1zquez","sequence":"first","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo Aldama","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin Quintas","family":"Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Department of Clinical Cardiology Cardiology, Hospital Universitario Marqu\u00e9s de Valdecilla Santander Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariana Varela","family":"Cancelo","sequence":"additional","affiliation":[{"name":"Department of Clinical Cardiology Cardiology, Complexo Hospitalario Universitario Ferrol (CHUF) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Rebollal","family":"Leal","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xacobe Flores","family":"Rios","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo Pi\u00f1\u00f3n","family":"Esteban","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge Salgado","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram\u00f3n Calvi\u00f1o","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Manuel V\u00e1zquez","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology Cardiology, Complexo Hospitalario Universitario A Coru\u00f1a (CHUAC) A Coru\u00f1a Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,20]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.06.012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.recesp.2021.11.023"},{"key":"e_1_2_8_4_1","doi-asserted-by":"crossref","unstructured":"TarantiniG TangG FovinoLN(2023).Management of coronary artery disease in patients undergoing transcatheter aortic valve implantation.A clinical consensus statement from the European Association of Percutaneous Cardiovascular Interventions in collaboration with the ESC Working Group on Cardiovascular 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