{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:15:53Z","timestamp":1783008953030,"version":"3.54.5"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T00:00:00Z","timestamp":1701043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Conduction disturbances and the need for permanent pacemaker (PPM) implantation remains a common complication for transcatheter aortic valve replacement (TAVR), particularly when self\u2010expanding (SE) valves are used.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>We compared in\u2010hospital and 30\u2010day rates of new PPM implantation between patients undergoing TAVR with SE valves using the conventional three\u2010cusp coplanar implantation technique and the cusp\u2010overlap technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively compared patients without a pre\u2010existing PPM who underwent a TAVR procedure with SE Evolut R or PRO valves using the cusp\u2010overlap technique from July 2018 to September 2020 (<jats:italic>n<\/jats:italic>\u2009=\u2009519) to patients who underwent TAVR using standard three\u2010cusp technique from April 2016 to March 2017 (<jats:italic>n<\/jats:italic>\u2009=\u2009128) in two high volume Canadian centers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was no significant difference in baseline RBBB between the groups (10.4% vs. 13.2; <jats:italic>p<\/jats:italic>\u2009=\u20090.35). The rate of in\u2010hospital new complete heart block (9.4% vs. 23.4%; <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001) and PPM implantation (8% vs. 21%; <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001) were significantly reduced when using the cusp\u2010overlap technique. The incidence of new LBBB (30.4% vs. 29%; <jats:italic>p<\/jats:italic>\u2009=\u20090.73) was similar. At 30 days, the rates of new complete heart block (11% vs. 23%; <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001) and PPM implantation (10% vs. 21%, <jats:italic>p<\/jats:italic>\u2009\u2264\u20090.001) remained significantly lower in the cusp\u2010overlap group, while the rate of new LBBB (35% vs. 30%; <jats:italic>p<\/jats:italic>\u2009=\u20090.73) was similar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Cusp\u2010overlap approach offers several potential technical advantages compared to standard three\u2010cusp view, and may result in lower PPM rates in TAVR with SE Evolut valve.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30910","type":"journal-article","created":{"date-parts":[[2023,11,27]],"date-time":"2023-11-27T23:49:29Z","timestamp":1701128969000},"page":"202-208","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cusp overlap method for self\u2010expanding transcatheter aortic valve replacement"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0735-9596","authenticated-orcid":false,"given":"Talal F.","family":"Aljabbary","sequence":"first","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Center University of Toronto Toronto Canada"},{"name":"Department of Cardiac Sciences, King Fahad Cardiac Center, College of Medicine King Saud University Riyadh Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikki","family":"Komatsu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Tokyo Medical University Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoki","family":"Ochiai","sequence":"additional","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Center University of Toronto Toronto Canada"},{"name":"Department of Cardiology Shonan Kamakura General Hospital Kamakura Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen E.","family":"Fremes","sequence":"additional","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Center University of Toronto Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noman","family":"Ali","sequence":"additional","affiliation":[{"name":"Division of Cardiology Terrence Donnelly Heart Center, St. Michael's Hospital, Unity Health Toronto, University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Burke","sequence":"additional","affiliation":[{"name":"Division of Cardiology Terrence Donnelly Heart Center, St. Michael's Hospital, Unity Health Toronto, University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Peterson","sequence":"additional","affiliation":[{"name":"Division of Cardiology Terrence Donnelly Heart Center, St. Michael's Hospital, Unity Health Toronto, University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1269-6733","authenticated-orcid":false,"given":"Neil P.","family":"Fam","sequence":"additional","affiliation":[{"name":"Division of Cardiology Terrence Donnelly Heart Center, St. Michael's Hospital, Unity Health Toronto, University of Toronto Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harindra C.","family":"Wijeysundera","sequence":"additional","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Center University of Toronto Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Radhakrishnan","sequence":"additional","affiliation":[{"name":"Schulich Heart Program, Sunnybrook Health Sciences Center University of Toronto Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,11,27]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.117.028352"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1816885"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.10.016"},{"key":"e_1_2_11_6_1","first-page":"1139","article-title":"A highly predictive risk model for pacemaker implantation after TAVR","volume":"10","author":"Maeno Y","year":"2017","journal-title":"JJACC Cardiovasc Interv"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2009.07.003"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.0088"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehz924"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.05.056"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.07.020"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.07.092"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.03.004"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.05.020"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.09.063"},{"key":"e_1_2_11_16_1","unstructured":"GrubbK. An optimized TAVR care pathway using Evolut PRO and PRO+ early results from the optimize PRO study. Presented at SCAI on April 2021.2021."},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/9991528"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,12]],"date-time":"2025-03-12T07:59:48Z","timestamp":1741766388000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11,27]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/ccd.30910"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30910","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,11,27]]},"assertion":[{"value":"2023-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}