{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,23]],"date-time":"2025-12-23T05:28:46Z","timestamp":1766467726966,"version":"3.38.0"},"reference-count":25,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:00:00Z","timestamp":1700611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Among the two stent strategies, contemporary evidence favors double kissing crush technique (DKC) for complex unprotected distal left main bifurcation (UdLMB) lesions. However one of the major challenges to these lesions is side branch (SB) restenosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>Our aim was to identify optical coherence tomographic (OCT) characteristics that may predict SB restenosis (SBR) after UdLMB angioplasty using DKC technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center, retrospective study that included 60 patients with complex UdLMB disease, who underwent OCT\u2010guided angioplasty using DKC technique. Angiographic follow\u2010up was performed in all patients at 1 year to identify patients with SBR. Patients with SBR group\u00a0were compared with patients without SBR\u00a0(NSBR group) for OCT parameters during index procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve (20%) patients developed SBR\u00a0at 1\u2010year follow\u2010up. The SBR group had longer SB lesion (18.8\u2009\u00b1\u20093.2 vs. 15.3\u2009\u00b1\u20093.7\u2009mm, <jats:italic>p<\/jats:italic>\u2009=\u20090.004) and neo\u2010metallic carinal length (2.1\u00a0vs. 0.1\u2009mm, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) when compared to the NSBR group. Longer neo\u2010metallic carinal length was associated with the absence of the dumbbell sign, presence of hanging stent struts across the SB ostium on OCT of final MB pullback. On multivariate regression analysis, SB distal reference diameter (DRD) and SB stent expansion were identified as independent predictors of SBR\u00a0with SB\u2010DRD of \u22642.8\u2009mm (area under curve\u20140.73, sensitivity\u201483.3%, and specificity\u201462.5%) and SB stent expansion of \u226489% (area under curve\u20140.88, sensitivity\u201483.3%, and\u00a0specificity\u2010 81.2%) as the best cut off values to predict SBR.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>SB DRD and SB stent expansion are the OCT predictors of future SBR\u00a0after UdLMB angioplasty using DKC technique.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30915","type":"journal-article","created":{"date-parts":[[2023,11,24]],"date-time":"2023-11-24T23:42:48Z","timestamp":1700869368000},"page":"51-60","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Optical Coherence Tomography Predictors of SIde Branch REstenosis after unprotected Left Main bifurcation angioplasty using double kissing crush technique (OP\u2010SIBRE LM Study)"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0631-8661","authenticated-orcid":false,"given":"Ankush","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Cardiology Army Institute of Cardiothoracic Sciences (AICTS) Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhinav","family":"Shrivastava","sequence":"additional","affiliation":[{"name":"Department of Cardiology Maharaja Agrasen Hospital New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanya","family":"Chhikara","sequence":"additional","affiliation":[{"name":"Department of Medicine Jacobi Medical Center Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mamas A.","family":"Mamas","sequence":"additional","affiliation":[{"name":"Keele Cardiovascular Research Group Keele University Keele UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5250-4735","authenticated-orcid":false,"given":"Rajesh","family":"Vijayvergiya","sequence":"additional","affiliation":[{"name":"Department of Cardiology Advanced Cardiac Center, PGIMER Chandigarh India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6323-0343","authenticated-orcid":false,"given":"Ajay","family":"Swamy","sequence":"additional","affiliation":[{"name":"KIMS Hospital Hyderabad India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nalin K.","family":"Mahesh","sequence":"additional","affiliation":[{"name":"St. Gregorios Medical Mission Hospital Parumala Kerala India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3690-2327","authenticated-orcid":false,"given":"Navreet","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Army Institute of Cardiothoracic Sciences (AICTS) Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Bajaj","sequence":"additional","affiliation":[{"name":"Department of Cardiology Army Institute of Cardiothoracic Sciences (AICTS) Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Balwinder","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Army Institute of Cardiothoracic Sciences (AICTS) Pune India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daulat Singh","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Cardiology J. 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