{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:14:10Z","timestamp":1792512850755,"version":"4.5.0"},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T00:00:00Z","timestamp":1701820800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Percutaneous pulmonary valve implantation (PPVI) with the self\u2010expandable Venus P\u2010valve system is a promising treatment for patients with pulmonary regurgitation (PR) and a native right ventricular outflow tract (RVOT). However, limited data is available regarding its midterm outcomes. This study assessed the midterm clinical and echocardiographic outcomes following Venus P\u2010valve implantation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 2013 to 2018, 55 patients with moderate or severe PR after surgical RVOT repair with a transannular or RVOT patch were consecutively enrolled from six hospitals in China. Five\u2010year clinical and echocardiographic outcomes were collected and evaluated. The primary endpoint was a freedom from all\u2010cause mortality and reintervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At 5 years, the primary endpoint was met for 96% of patients, corresponding to a freedom from all\u2010cause mortality of 96% (95% confidence interval [CI]: 86%\u221299%) and freedom from reintervention of 98% (95% CI: 87%\u2212100%). Endocarditis was reported in five patients (four patients within 1 year and one patient at 5 years) following PPVI. Transpulmonary gradient and stent orifice diameter remained stable compared to at discharge (\n                      <jats:italic>p<\/jats:italic>\n                      \uff1e0.05). No paravalvular leak was reported while only 1 patient gradually increased to moderate PR during follow\u2010up. Significant improvement of RV diameter and LVEF\u00a0(\n                      <jats:italic>p<\/jats:italic>\n                      \uff1c0.001) sustained over the 5\u2010year follow\u2010up, in consistent with remarked improved New York Heart Association(NYHA) functional class (\n                      <jats:italic>p<\/jats:italic>\n                      \uff1c0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The 5\u2010year results of the China VenusP Study demonstrated the midterm benefits of Venus P\u2010valve implantation in the management of patients with severe PR with an enlarged native RVOT by providing sustained symptomatic and hemodynamic improvement.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.30916","type":"journal-article","created":{"date-parts":[[2023,12,6]],"date-time":"2023-12-06T05:24:21Z","timestamp":1701840261000},"page":"359-366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Five\u2010year follow\u2010up after percutaneous pulmonary valve implantation using the Venus P\u2010valve system for patients with pulmonary regurgitation and an enlarged native right ventricular outflow tract"],"prefix":"10.1002","volume":"103","author":[{"given":"Qinchun","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Cardiology Fuwai Hospital Chinese Academy of Medical Sciences Beijing China"},{"name":"Department of Cardiology, Zhongshan Hospital Shanghai Institute of Cardiovascular Diseases, Fudan University Shanghai 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