{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:59:02Z","timestamp":1758056342682,"version":"3.44.0"},"reference-count":5,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Key points<\/jats:title><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>Patients with severe chronic kidney disease (CKD) and nonvalvular atrial fibrillation are underrepresented in left atrial appendage occlusion (LAAO) studies, despite their higher fragility and greater intolerance to antithrombotic therapy.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>LAAO appears to be safe and effective in reducing thromboembolic and bleeding recurrences both in patients with and without advanced CKD.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Despite favorable ischemic and bleeding outcomes, patients with severe CKD experienced higher mortality rate, compared to those without severe CKD<\/jats:p><\/jats:list-item><\/jats:list><\/jats:p>","DOI":"10.1002\/ccd.30980","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T03:21:56Z","timestamp":1708399316000},"page":"684-685","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Left atrial appendage closure and advanced chronic kidney disease: Another string to the bow"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1259-5163","authenticated-orcid":false,"given":"Gianpiero","family":"D'Amico","sequence":"first","affiliation":[{"name":"Cardiology Unit, Department of Cardio\u2010Thoracic, Vascular Medicine and Intensive Care Ospedale dell'Angelo, Mestre Venezia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2293-8270","authenticated-orcid":false,"given":"Francesco","family":"Gallo","sequence":"additional","affiliation":[{"name":"Cardiology Unit, Department of Cardio\u2010Thoracic, Vascular Medicine and Intensive Care Ospedale dell'Angelo, Mestre Venezia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,20]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy060"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30946"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30629"},{"key":"e_1_2_3_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.07.052"},{"key":"e_1_2_3_6_1","doi-asserted-by":"crossref","unstructured":"Flores\u2010UmanzorE AsgharA Cepas\u2010Guill\u00e9nPL et al.Transcatheter left atrial appendage occlusion in patients with chronic kidney disease: a systematic review and meta\u2010analysis.Clin Res Cardiol. Published Online December 19 2023.https:\/\/doi:10.1007\/s00392-023-02359-1","DOI":"10.1007\/s00392-023-02359-1"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.30980","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T11:40:54Z","timestamp":1757936454000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.30980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":5,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1002\/ccd.30980"],"URL":"https:\/\/doi.org\/10.1002\/ccd.30980","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2024,2,20]]},"assertion":[{"value":"2024-02-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}