{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T20:59:11Z","timestamp":1758056351777,"version":"3.44.0"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The use of the Indigo CAT RX Aspiration System (Penumbra Inc.) during percutaneous coronary intervention has received limited study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively examined the clinical, angiographic, and procedural characteristics, outcomes, and follow\u2010up of patients who underwent mechanical aspiration thrombectomy with the Indigo CAT RX system (Penumbra Inc.) at a large tertiary care hospital between January 2019 and April 2023.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the study period, 83 patients (85 lesions) underwent thrombectomy with the Indigo CAT RX. Mean patient age was 64.9\u2009\u00b1\u200914.48 years and 31.2% were women. The most common presentations were ST\u2010segment elevation myocardial infarction (MI) (66.2%) and non\u2010ST\u2010segment elevation MI (26.5%). A final thrombolysis in MI flow grade of 3 and final myocardial blush grade of 3 were achieved in 76% and 46% of the cases, respectively. Technical success was achieved in 88.9% of the cases that included Indigo CAT RX treatment only, compared with 57.1% of the cases that also included manual aspiration. There were no device\u2010related serious adverse events. At 30\u2010day postprocedure, the incidence of major adverse cardiac events (composite of cardiovascular death, recurrent MI, cardiogenic shock, new or worsening New York Heart Association Class IV heart failure, stroke) was 8.5%: 1.3% stroke (postprocedure, in\u2010hospital), 1.3% MI, 6.1% cardiac death, and 7.5% developed cardiogenic shock.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Use of the Indigo CAT RX system is associated with high technical success and acceptable risk of complications, including stroke.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.30994","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T02:16:29Z","timestamp":1709172989000},"page":"695-702","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Use of the Indigo CAT RX aspiration system during percutaneous coronary intervention"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2345-3040","authenticated-orcid":false,"given":"Sydney","family":"Peng","sequence":"first","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2683-5255","authenticated-orcid":false,"given":"Athanasios","family":"Rempakos","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6991-7621","authenticated-orcid":false,"given":"Olga C.","family":"Mastrodemos","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bavana V.","family":"Rangan","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9549-0748","authenticated-orcid":false,"given":"Michaella","family":"Alexandrou","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1069-2437","authenticated-orcid":false,"given":"Salman","family":"Allana","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1481-8044","authenticated-orcid":false,"given":"Ahmed","family":"Al\u2010Ogaili","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deniz","family":"Mutlu","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Karacsonyi","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seth","family":"Bergstedt","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhmmad S.","family":"Khalid","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Stanberry","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9416-9701","authenticated-orcid":false,"given":"Emmanouil S.","family":"Brilakis","sequence":"additional","affiliation":[{"name":"Allina Health Minneapolis Heart Institute and Minneapolis Heart Institute Foundation Minneapolis Minnesota USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.04.057"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.742312"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706416"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1308789"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415098"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025371"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.122.012433"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2019.103208"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2008.08.010"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.21.2550"},{"key":"e_1_2_9_12_1","doi-asserted-by":"crossref","unstructured":"TIMI 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