{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:55:18Z","timestamp":1783464918228,"version":"3.55.0"},"reference-count":36,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T00:00:00Z","timestamp":1709078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Pulmonary hypertension (PH) and right ventricular dysfunction\u00a0are poor prognostic predictors in patients underwent transcatheter aortic valve implantation (TAVI) for severe aortic stenosis (AS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The prognostic impact of the main pulmonary artery\/ascending aorta diameter ratio (MPA\/AOr), measured simply by computed\u2010tomographic angiography (CTA), was investigated in this patient group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 374 retrospectively evaluated patients (mean age 78.1\u2009\u00b1\u20098.4 years, 192 [51.3%]\u00a0females)\u00a0who underwent TAVI for severe AS were included. MPA\/AOr was measured on preprocedural CTA in all patients and the effect of this measurement on the presence of PH, in\u2010hospital and 2\u2010year\u2010overall long\u2010term mortality was investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The presence of PH was defined as a systolic pulmonary artery pressure (sPAP) &gt;42\u2009mmHg measured by echocardiography. According to multivariate\u2010logistic\u2010regression analysis, MPA\/AOr\u00a0(adjusted [Adj] odds ratio [OR]: 1.188, confidence interval [CI] 95% [1.002\u20131.410], <jats:italic>p<\/jats:italic>\u2009=\u20090.048), tricuspid annular plane systolic excursion (TAPSE)\u00a0(adj OR:0.736, CI 95% [0.663\u20130.816], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001)\u00a0and left atrial diameter (adj OR:1.051, CI 95% [1.007\u20131.098], <jats:italic>p<\/jats:italic>\u2009=\u20090.024)\u00a0were identified as independent predictors of PH. In addition, a statistically significant correlation was found between MPA\/AOr and TAPSE (<jats:italic>r<\/jats:italic>: \u22120.283, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). Furthermore, MPA\/AOr was found to be an independent predictor of both in\u2010hospital (adj OR:1.434, CI 95% [1.093\u20131.881], <jats:italic>p<\/jats:italic>\u2009=\u20090.009)\u00a0and 2\u2010year long\u2010term (adj OR:1.518, CI 95% [1.243\u20131.853], <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001)\u00a0mortality in multivariate analysis including TAPSE, STS score and sPAP. In the 2\u2010year Kaplan\u2013Meier survival probability analysis, an MPA\/AOr &gt;0.86 was found to have a\u00a0hazard ratio\u00a0of 3.697 (95% CI: 2.341\u20135.840), with a log\u2010rank <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>MPA\/AOr, which can be measured simply by CTA, may be useful as an indicator of the presence of PH and poor prognosis in patients planned for TAVI for severe AS.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31000","type":"journal-article","created":{"date-parts":[[2024,2,28]],"date-time":"2024-02-28T06:00:38Z","timestamp":1709100038000},"page":"782-791","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic impact of main pulmonary artery to ascending aorta diameter ratio in patients with severe aortic stenosis underwent transcatheter aortic valve 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