{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T19:25:59Z","timestamp":1791314759587,"version":"4.3.1"},"reference-count":14,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Utilization of right ventricular mechanical circulatory support (RV\u2010MCS) devices has been limited by a lack of recognition of RV failure as well as a lack of availability and experience with RV\u2010MCS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>We report a single\u2010center experience with the use of percutaneous RV\u2010MCS and report predictors of adverse outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This was a single\u2010center retrospective cohort study. Data from consecutive patients who received RV\u2010MCS for any indication between June 2015 and January 2022 were included. Data on baseline comorbidities, hemodynamics, and laboratory values were collected. The primary outcome was in\u2010hospital mortality analyzed as a logistic outcome in a multivariable model. These variables were further ranked by their predictive value.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 58 consecutive patients enrolled, the median age was 66 years, 31% were female and 53% were white. The majority of the patients (48%) were hospitalized for acute on chronic heart failure. The majority of the patients were SCAI SHOCK Stage D (67%) and 34 (64%) patients had MCS placed within 24\u2009h of the onset of shock. Before placement of RV\u2010MCS, median central venous pressure (CVP) and RV stroke work index were 20\u2009mmHg and 8.9\u2009g\u2009m\/m<jats:sup>2<\/jats:sup>, respectively. Median serum lactate was 3.5 (1.6, 6.2)\u2009mmol\/L. Impella RP was implanted in 50% and ProtekDuo in the remaining 50%. Left ventricular MCS was concomitantly used in 66% of patients. Twenty\u2010eight patients (48.3%) died. In these patients, median serum lactate was significantly higher (4.1 [2.3, 13.0] vs. 2.2 [1.4, 4.0]\u2009 mmol\/L, <jats:italic>p<\/jats:italic>\u2009=\u20090.007) and a trend toward higher median CVP (24 [18, 31] vs. 19 [14, 24] mmHg, <jats:italic>p<\/jats:italic>\u2009=\u20090.052). In the multivariable logistic model, both serum lactate and CVP before RV\u2010MCS placement were independent predictors of in\u2010hospital mortality. Serum lactate had the highest predictive value.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our real\u2010world cohort, 52% of patients treated with RV\u2010MCS survived their index hospitalization. Serum lactate at presentation and CVP were the strongest predictors of in\u2010hospital mortality.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31018","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T04:00:13Z","timestamp":1712548813000},"page":"909-916","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Use of percutaneous mechanical circulatory support for right ventricular failure"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9476-9264","authenticated-orcid":false,"given":"Kartik","family":"Gupta","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Lemor","sequence":"additional","affiliation":[{"name":"Division of Cardiology University of Mississippi Medical Center Jackson Mississippi USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Alkhatib","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine University of Kansas Medical Center Kansas City Kansas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"McBride","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Cowger","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gillian","family":"Grafton","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1368-5320","authenticated-orcid":false,"given":"Khaldoon","family":"Alaswad","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"O'Neill","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Villablanca","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3486-6753","authenticated-orcid":false,"given":"Mir B.","family":"Basir","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Diseases Henry Ford Hospital Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2013.08.007"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2013.10.015"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2013.01.007"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2018.2454"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(97)00780-7"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2018.08.001"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2018.12.005"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2014.02.028"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.025290"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.01.018"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2020.11.027"},{"key":"e_1_2_8_13_1","unstructured":"U.S. Food and Drug Administration. Impella RP system post\u2010approval study results and updated labeling\u2014letter to health care providers. FDA. December 5 2022. Accessed September 21 2023.https:\/\/www.fda.gov\/medical\u2010devices\/letters\u2010health\u2010care\u2010providers\/update\u2010impella\u2010rp\u2010system\u2010post\u2010approval\u2010study\u2010results\u2010and\u2010updated\u2010labeling\u2010letter\u2010health\u2010care"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm12091481"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29493"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,16]],"date-time":"2025-09-16T07:48:04Z","timestamp":1758008884000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,8]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1002\/ccd.31018"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31018","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,8]]},"assertion":[{"value":"2023-10-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}