{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T19:52:15Z","timestamp":1786477935147,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T00:00:00Z","timestamp":1712275200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Bicuspid aortic valve (BAV) stenosis is a complex anatomical scenario for transcatheter aortic valve implantation (TAVI). Favorable short\u2010term clinical outcomes have been reported with TAVI in this setting, but long\u2010term data are scarce.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively included, in a single\u2010center registry, patients with BAV stenosis who underwent TAVI before 2020. We compared patients treated with self\u2010expanding valves (SEV) versus balloon\u2010expandable valves (BEV). The primary endpoint was a composite of all\u2010cause mortality, stroke and need for aortic valve (AV) reintervention at 3 years. Secondary endpoints included each component of the primary endpoint, cardiovascular mortality, permanent pacemaker implantation (PPI) rate, mean gradient and \u2265moderate paravalvular leak (PVL) rate.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 150 consecutive patients (SEV\u2009=\u200983, BEV\u2009=\u200967) were included. No significant differences were reported between SEV and BEV groups for the primary composite endpoint (SEV 35.9% vs. BEV 32%, <jats:italic>p<\/jats:italic>\u2009=\u20090.66), neither for clinical secondary endpoints (all\u2010cause mortality SEV 28.1% vs. BEV 28%, <jats:italic>p<\/jats:italic>\u2009=\u20090.988; cardiovascular mortality SEV 14.1% vs. BEV 20%, <jats:italic>p<\/jats:italic>\u2009=\u20090.399; stroke SEV 12.5% vs. BEV 6%, <jats:italic>p<\/jats:italic>\u2009=\u20090.342; need for AV reintervention SEV 0% vs. BEV 0%; PPI SEV 28.1% vs. BEV 24%, <jats:italic>p<\/jats:italic>\u2009=\u20090.620). A lower mean gradient persisted up to 3 years in the SEV group (SEV 8.8\u2009\u00b1\u20093.8\u2009mmHg vs. BEV 10.7\u2009\u00b1\u20093.2\u2009mmHg, <jats:italic>p<\/jats:italic>\u2009=\u20090.063), while no significant difference was found in the rate of \u2265 moderate PVL (SEV 3\/30 vs. BEV 0\/25, <jats:italic>p<\/jats:italic>\u2009=\u20090.242).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In this single center registry, we observed favorable 3\u2010year clinical outcomes in nonselected BAV patients treated with different generation devices, without significant differences between patients receiving SEV or BEV.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31041","type":"journal-article","created":{"date-parts":[[2024,4,5]],"date-time":"2024-04-05T07:00:00Z","timestamp":1712300400000},"page":"1004-1014","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three\u2010year clinical outcomes after transcatheter aortic valve implantation in patients with bicuspid aortic disease: Comparison between self\u2010expanding and balloon\u2010expandable valves"],"prefix":"10.1002","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8414-0726","authenticated-orcid":false,"given":"Mauro","family":"Boiago","sequence":"first","affiliation":[{"name":"Groupe CardioVasculaire Interventionnel Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Bellamoli","sequence":"additional","affiliation":[{"name":"Groupe CardioVasculaire Interventionnel Clinique Pasteur Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2661-3246","authenticated-orcid":false,"given":"Chiara","family":"De Biase","sequence":"additional","affiliation":[{"name":"Groupe CardioVasculaire Interventionnel Clinique Pasteur Toulouse 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