{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T05:19:40Z","timestamp":1736918380755,"version":"3.33.0"},"reference-count":25,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:00:00Z","timestamp":1722384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Paravalvular leakage (PVL) is a common complication after artificial valve replacement. Transcatheter paravalvular leak closure (PVT), an efficient, safe, and minimally invasive treatment for PVL patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>The purpose of this study was to present our experience with transcatheter closure of mitral paravalvular leakage (PVL) after surgical valve replacement in our center.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cohort of 81 consecutive patients with mitral PVLs was treated with transcatheter closure between September 2014 and December 2022. We reviewed the demographics, clinical features, therapeutic modalities and follow\u2010up results. The patients' charts were used for retrospective analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Eighty\u2010one patients from one center were enrolled in this study. The median age of the patients was 63\u2009\u00b1\u200911 years. The median LVEF was 51%\u2009\u00b1\u20097%, and the median regurgitation volume was 11.5\u2009\u00b1\u200910.1\u2009mL. Sealing with occlusion was successful in 70 patients, and the technical success rate was 86.5%. The median regurgitation volume was reduced to 1.95\u2009\u00b1\u20092.6\u2009mL. The major adverse event was hemolysis, which affected 19 patients, 17 of whom required blood transfusion. Three patients required secondary open surgery due to bleeding. Three patients died during the hospital stay, and all of their deaths were caused by hemolysis\u2010related complications. The median hospital stay was 10.3\u2009\u00b1\u20096.3 days. During the follow\u2010up period, 2 patients died, and none of their deaths were caused by surgery. The New York Heart Association classification increased in all patients during the 6\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Transcatheter mitral PVL closure requires complex catheter techniques. However, this technique is minimally invasive and has a shorter hospital stay. Interventional mitral PVL closure is a safe and efficacious technique for high\u2010risk surgical patients with symptomatic paravalvular regurgitation.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31135","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T10:56:31Z","timestamp":1722423391000},"page":"1499-1507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Transcatheter closure management of mitral paravalvular leakage: A single center experience"],"prefix":"10.1002","volume":"104","author":[{"given":"Yue","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardio\u2010Vascular Surgery Air Force Medical Center of People's Liberation Army Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ping","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Mao","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengen","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Xijing Hospital, Air Force Medical University Xi'an China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.12.060"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01361-4"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2006.09.019"},{"issue":"6","key":"e_1_2_8_5_1","first-page":"792","article-title":"Early and late results of the surgical correction of cardiac prosthetic paravalvular leaks","volume":"14","author":"Akins CW","year":"2005","journal-title":"J Heart Valve Dis"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000439247"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2017.07.046"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2014.12.041"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(92)90250-Q"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2014.01.159"},{"issue":"3","key":"e_1_2_8_11_1","first-page":"238","article-title":"Efficacy of interventional therapy on paravalvular leakage after mitral valve replacement","volume":"44","author":"Xu CN","year":"2016","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2011.11.007"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/1195613"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.116.022684"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27371"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1639334"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.750896"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8191.2007.00449.x"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY14M05_01"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2014.12.012"},{"issue":"2","key":"e_1_2_8_21_1","first-page":"128","article-title":"Transcatheter closure of paravalvular leaks using a paravalvular leak device \u2010 a prospective Polish registry","volume":"2","author":"Smolka G","year":"2016","journal-title":"Adv Interv Cardiol"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.07.041"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeu105"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/aor.13504"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2019.06.016"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw165"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31135","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T12:11:41Z","timestamp":1736856701000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,31]]},"references-count":25,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1002\/ccd.31135"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31135","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2024,7,31]]},"assertion":[{"value":"2024-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}