{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T17:13:55Z","timestamp":1775322835447,"version":"3.50.1"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,7,20]],"date-time":"2024-07-20T00:00:00Z","timestamp":1721433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005035","name":"Biotronik","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Although covered stents (CS) represent a potentially life\u2010saving intervention for coronary perforation (CAP), their application has expanded to other contexts, including coronary aneurysms (CAA). However, data regarding mid\u2010 and long\u2010term outcomes of CS in these settings scenarios remains limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>This meta\u2010analysis aims to evaluate major adverse cardiac events (MACE) from discharge through long\u2010term follow\u2010up in patients undergoing percutaneous coronary intervention with the new generation polyurethane\u2010covered cobalt\u2010chromium PK Papyrus CS.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We conducted a meta\u2010analysis of data from three observational trials that included long\u2010term follow\u2010up of patients who underwent PK Papyrus CS implantation: Papyrus\u2010Spain, SOS PK Papyrus, and PAST\u2010PERF registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>332 patients underwent PK Papyrus CS implantation, 236 (71.1%) for CAP, 70 (21.1%) for CAA and 26 (7.8%) for other indications. After a mean follow\u2010up of 16.2 months, the MACE was 14.3%, with Target Lesion Revascularization (TLR) being the most frequent (8.5%), followed by stent thrombosis (ST), 3.3% and cardiac death (CD), 2.6%. Comparing CAP and CAA subgroups, the MACE rate in CAA was significantly higher than CAP (21.4% vs 9.7%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.01), primary driven by ST (CAA: 8.6% vs CAP: 1.3%; <jats:italic>p<\/jats:italic>\u2009=\u20090.0015).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The clinical outcomes following PK Papyrus CS implantation are deemed acceptable, considering the challenging scenarios and the existing alternative treatments. However, MACE rates in patients with CAA who received Papyrus PK CS were significantly higher than in those with CAP, underscoring the importance of meticulous patient selection and optimization of CS in these complex patients and coronary anatomies.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31157","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T05:39:05Z","timestamp":1721540345000},"page":"492-498","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Meta\u2010long Papyrus: Meta\u2010analysis of mid to long\u2010term outcomes of PK Papyrus covered stent"],"prefix":"10.1002","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6362-7618","authenticated-orcid":false,"given":"Alfonso","family":"Jurado\u2010Rom\u00e1n","sequence":"first","affiliation":[{"name":"Cardiology Department La Paz University Hospital Madrid Spain"},{"name":"Hospital La Paz Institute for Health 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i Pujol University Hospital Barcelona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radu","family":"Spinu","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Of Annecy Cannes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lo\u00efc","family":"Belle","sequence":"additional","affiliation":[{"name":"Cardiology Department Hospital Of Annecy Cannes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guillermo","family":"Galeote","sequence":"additional","affiliation":[{"name":"Cardiology Department La Paz University Hospital Madrid Spain"},{"name":"Hospital La Paz Institute for Health Research, IdiPAZ Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Santiago","family":"Jim\u00e9nez\u2010Valero","sequence":"additional","affiliation":[{"name":"Cardiology Department La Paz University Hospital Madrid Spain"},{"name":"Hospital La Paz Institute for Health Research, IdiPAZ 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