{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T14:03:14Z","timestamp":1785247394086,"version":"3.55.0"},"reference-count":25,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T00:00:00Z","timestamp":1722297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>We aimed to evaluate transcatheter mitral valve implantation (TMVI) using predominantly balloon\u2010expandable transcatheter heart valves (THV) in patients with a landing zone for a percutaneously delivered prosthesis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with a degenerated mitral valve bioprosthesis, annuloplasty ring, and mitral annulus calcification (MAC) considered at high surgical risk currently represent a treatment challenge. TMVI is an alternative treatment option.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Retrospective analysis of patients with symptomatic degenerated mitral valve bioprosthesis, or annuloplasty ring, and MAC treated with TMVI between November 2011 and April 2021. Endpoints were defined according to Mitral Valve Academic Research Consortium (MVARC) criteria and included device and procedure success at 30 days as well as mortality at 30 days and 1 year after the procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 77 patients underwent TMVI (valve in valve [ViV\u2009=\u200956], valve in ring [ViR\u2009=\u200911], and valve in MAC [ViMAC\u2009=\u200910]). There was a trend toward higher technical success (all\u2009=\u200993.5%, ViV\u2009=\u200996.4%, ViR\u2009=\u200990.9%, ViMAC\u2009=\u200980%, <jats:italic>p<\/jats:italic>\u2009=\u20090.06) and lower 30\u2010day (all\u2009=\u200911.7%, ViV\u2009=\u200910.7%, ViR\u2009=\u20099.1%, ViMAC\u2009=\u200920%, <jats:italic>p<\/jats:italic>\u2009=\u20090.49) and 1\u2010year mortality (all\u2009=\u200926%, ViV\u2009=\u200923.2%, ViR\u2009=\u200927.3%, ViMAC=\u200940%, <jats:italic>p<\/jats:italic>\u2009=\u20090.36) after ViV and ViR compared to ViMAC.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>TMVI represents a reasonable treatment option in selected patients with MAC or who are poor candidates for redo mitral valve surgery. Technical success and survival up to 1 year were not significantly dependent on the subgroup in which TMVI was performed.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31166","type":"journal-article","created":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T09:23:58Z","timestamp":1722331438000},"page":"837-852","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Outcomes after transcatheter mitral valve implantation in valve\u2010in\u2010valve, valve\u2010in\u2010ring, and valve\u2010in\u2010mitral annular calcification"],"prefix":"10.1002","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0505-9530","authenticated-orcid":false,"given":"Hector A.","family":"Alvarez\u2010Covarrubias","sequence":"first","affiliation":[{"name":"Department of Cardiology, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"},{"name":"Departamento de Cardiolog\u00eda Hospital de Cardiolog\u00eda, Centro M\u00e9dico Nacional Siglo XXI, IMSS Mexico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Joner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"},{"name":"DZHK (German Center for Cardiovascular Research) Partner Site Munich Heart Alliance Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Lutz","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0728-2819","authenticated-orcid":false,"given":"Erion","family":"Xhepa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"},{"name":"DZHK (German Center for Cardiovascular Research) Partner Site Munich Heart Alliance Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3549-3007","authenticated-orcid":false,"given":"N. Patrick","family":"Mayr","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr An\u00e4sthesiologie, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Lachmann","sequence":"additional","affiliation":[{"name":"First Department of Medicine, Klinikum rechts der Isar Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8668-4313","authenticated-orcid":false,"given":"Salvatore","family":"Cassese","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Deutsches Herzzentrum M\u00fcnchen Technische Universit\u00e4t M\u00fcnchen Munich Germany"},{"name":"DZHK (German Center for Cardiovascular Research) Partner Site Munich Heart Alliance Munich 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