{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:52:22Z","timestamp":1779879142125,"version":"3.53.1"},"reference-count":16,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T00:00:00Z","timestamp":1726358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,9,15]],"date-time":"2024-09-15T00:00:00Z","timestamp":1726358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The VASCADE MVP venous vascular closure system is commonly used for percutaneous venotomy closure in catheter\u2010based procedures utilizing sheath sizes 6\u201012 French. However, its application with larger sheaths such as ones required in left atrial appendage occlusion (LAAO) has yet to be explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study compared the efficacy and safety of VASCADE MVP versus conventional Figure\u2010of\u20108 sutures (Fo8) for femoral venotomy closure in patients undergoing Watchman LAAO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single\u2010center retrospective analysis included patients who underwent post\u2010LAAO femoral venotomy closure with either VASCADE MVP or Fo8 sutures. The primary efficacy endpoint was time to hemostasis (TTH). Primary safety endpoints were 30\u2010day access site\u2010related readmissions and major complications. Minor access\u2010site\u2010related complications were also assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      107 patients underwent post\u2010LAAO femoral venotomy closure with VASCADE MVP, of which 101 were successful (94.4%). 99 patients underwent conventional closure with Fo8 sutures and supplemental manual pressure. Baseline characteristics were similar between groups. TTH was significantly shorter with VASCADE MVP (152.9 vs. 335.8\u2009s,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). Major safety outcomes were comparable. However, the conventional group experienced a higher incidence of ecchymosis (16.2% vs 4.7%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) and 30\u2010day all\u2010cause readmission (18.2% vs 8.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>VASCADE MVP significantly reduced TTH compared to Fo8 sutures after LAAO. While demonstrating a similar safety profile, VASCADE MVP may offer a more efficient approach to femoral vein closure in this patient population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31209","type":"journal-article","created":{"date-parts":[[2024,9,16]],"date-time":"2024-09-16T00:40:32Z","timestamp":1726447232000},"page":"1260-1266","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy and safety of the VASCADE\u00ae MVP venous vascular closure device in patients undergoing percutaneous left atrial appendage occlusion with WATCHMAN"],"prefix":"10.1002","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2932-6525","authenticated-orcid":false,"given":"Hafez","family":"Golzarian","sequence":"first","affiliation":[{"name":"Internal Medicine Residency Program Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"},{"name":"Department of Cardiovascular Disease HCA Houston Healthcare \u2013 Kingwood\/University of Houston College of Medicine Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine T.","family":"Graebel","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency Program Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Bailey","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency Program Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Widmer","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency Program Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arielle","family":"Thiel","sequence":"additional","affiliation":[{"name":"Structural Heart &amp; Intervention Center Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerri","family":"Hempfling","sequence":"additional","affiliation":[{"name":"Structural Heart &amp; Intervention Center Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Otto","sequence":"additional","affiliation":[{"name":"Structural Heart &amp; Intervention Center Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd","family":"Otto","sequence":"additional","affiliation":[{"name":"Structural Heart &amp; Intervention Center Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1912-943X","authenticated-orcid":false,"given":"Sandeep M.","family":"Patel","sequence":"additional","affiliation":[{"name":"Structural Heart &amp; Intervention Center Mercy Health\u2014St. Rita's Medical Center Lima Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,15]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.14804"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2017.05.005"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29077"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.07.028"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2018.05.019"},{"issue":"7","key":"e_1_2_11_7_1","first-page":"175","article-title":"Review of vascular closure devices","volume":"19","author":"Schwartz BG","year":"2011","journal-title":"J Invas Cardiol"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacep.2019.08.013"},{"issue":"3","key":"e_1_2_11_9_1","first-page":"129","article-title":"A prospective, randomized, pivotal trial of a novel extravascular collagen\u2010based closure device compared to manual compression in diagnostic and interventional patients","volume":"27","author":"Hermiller JB","year":"2015","journal-title":"J Invasive Cardiol"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1393972"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27886"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euv375"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-015-0036-y"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ipej.2017.02.003"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.24835"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.20190"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euz004"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.31209","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T08:17:39Z","timestamp":1777709859000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,15]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1002\/ccd.31209"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31209","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,15]]},"assertion":[{"value":"2024-01-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}