{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T11:07:12Z","timestamp":1785150432470,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transcatheter mitral valve replacement (TMVR) is emerging in the context of annular calcification (valve\u2010in\u2010MAC; ViMAC), failing surgical mitral annuloplasty (mitral\u2010valve\u2010in\u2010ring; MViR) and failing mitral bioprosthesis (mitral\u2010valve\u2010in\u2010valve; MViV). A notorious risk of TMVR is neo left ventricular outflow tract (neo\u2010LVOT) obstruction. Three\u2010dimensional computational models (3DCM) are derived from multi\u2010slice computed tomography (MSCT) and aim to predict neo\u2010LVOT area after TMVR. Little is known about the accuracy of these neo\u2010LVOT predictions for various mitral phenotypes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Preprocedural 3DCMs were created for ViMAC, MViR and MViV cases. Throughout the cardiac cycle, neo\u2010LVOT dimensions were semi\u2010automatically calculated on the 3DCMs. We compared the predicted neo\u2010LVOT area on the preprocedural 3DCM with the actual neo\u2010LVOT as measured on the post\u2010procedural MSCT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Across 12 TMVR cases and examining 20%\u201370% of the cardiac phase, the mean difference between predicted and post\u2010TMVR neo\u2010LVOT area was \u221223\u2009\u00b1\u200928 mm\n                      <jats:sup>2<\/jats:sup>\n                      for MViR, \u221221\u2009\u00b1\u200934 mm\n                      <jats:sup>2<\/jats:sup>\n                      for MViV and \u221273\u2009\u00b1\u200961 mm\n                      <jats:sup>2<\/jats:sup>\n                      for ViMAC. The mean intra\u2010class correlation coefficient for absolute agreement between predicted and post\u2010procedural neo\u2010LVOT area (throughout the whole cardiac cycle) was 0.89 (95% CI 0.82\u20130.94,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) for MViR, 0.81 (95% CI 0.62\u20130.89,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) for MViV, and 0.41 (95% CI 0.12\u20130.58,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002\n                      <jats:italic>)<\/jats:italic>\n                      for ViMAC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Three\u2010dimensional computational models accurately predict neo\u2010LVOT dimensions post TMVR in MViR and MViV but not in ViMAC. Further research should incorporate device host interactions and the effect of changing hemodynamics in these simulations to enhance accuracy in all mitral phenotypes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31287","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T02:40:52Z","timestamp":1730947252000},"page":"249-257","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Accuracy of Three\u2010Dimensional Neo Left Ventricular Outflow Tract Simulations With Transcatheter Mitral Valve Replacement in Different Mitral Phenotypes"],"prefix":"10.1002","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-2124-109X","authenticated-orcid":false,"given":"Mark M. P.","family":"van den Dorpel","sequence":"first","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Uchoa","family":"de Assis","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Cardiology Amphia Ziekenhuis Breda The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenna","family":"van Niekerk","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rutger\u2010Jan","family":"Nuis","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9081-5518","authenticated-orcid":false,"given":"Joost","family":"Daemen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire Ben","family":"Ren","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Hirsch","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Kardys","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben J. L.","family":"van den Branden","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Budde","sequence":"additional","affiliation":[{"name":"Department of Radiology and Nuclear Medicine Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2732-1205","authenticated-orcid":false,"given":"Nicolas M.","family":"Van Mieghem","sequence":"additional","affiliation":[{"name":"Department of Cardiology Thoraxcenter, Cardiovascular Institute, Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.09.037"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.06.041"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.12.001"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.09.027"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.27447"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.06.015"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2021.05.002"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.01.052"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.005331"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2015.05.008"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiomech.2018.02.017"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005344"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30816"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.05.064"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10237-020-01304-9"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.shj.2022.100032"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2005.01.023"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13239-019-00427-0"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31287","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.31287","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T08:35:28Z","timestamp":1772958928000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,6]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/ccd.31287"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31287","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,6]]},"assertion":[{"value":"2024-08-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}