{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T02:10:28Z","timestamp":1740103828558,"version":"3.37.3"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Saphenous vein graft percutaneous coronary intervention (SVG\u2010PCI) is a relatively common procedure in patients after coronary artery bypass grafting (CABG). Although internal mammary artery is considered optimal, SVG is still used in the majority of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>Investigating the potential role of gender differences in the incidence and outcomes of SVG\u2010PCI.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The study was based on a prospectively collected registry of 1199 consecutive patients (169 female) who underwent SVG\u2010PCI in a tertiary medical center between 2004 and 2023. Primary outcomes included MACE (death, myocardial infarction [MI], target vessel revascularization [TVR], stroke) and mortality, at 1 and 3 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Female patients were older (73.6\u2009\u00b1\u20099.1 years vs. 70.6\u2009\u00b1\u20099.7 years, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), suffered from higher rates of diabetes mellitus, peripheral vascular disease, and congestive heart failure (78.1% vs. 61.3% <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001, 13.6% vs. 7% <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.003, 66.3% vs.\u200951.8% <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001 respectively). Additionally, female patients had lower trans\u2010radial access use (11.9% vs. 19.3%, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.025), and underwent SVG\u2010PCI earlier following their CABG procedure (11.3\u2009\u00b1\u20096.2 years vs 12.9\u2009\u00b1\u20096.1 years, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.003), as compared to male patients. There were no differences in MACE rates between the groups. Mortality was higher in the female group at 1 year (13.6% vs. 6.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.003), but no significant differences were observed at 3 years (24.3% vs. 20.9%, <jats:italic>p<\/jats:italic>\u2009=\u20090.320). Cox regression analysis identified age, renal function, ejection fraction, MI and trans\u2010femoral as independent risk factors for mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Gender\u2010specific monitoring and early intervention, especially for women, are required for better management of graft patency, potentially improving long\u2010term outcomes.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31336","type":"journal-article","created":{"date-parts":[[2024,12,11]],"date-time":"2024-12-11T07:30:52Z","timestamp":1733902252000},"page":"456-463","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Gender\u2010Related Outcomes in Saphenous Vein Graft Interventions"],"prefix":"10.1002","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6067-6342","authenticated-orcid":false,"given":"Azriel","family":"Osherov","sequence":"first","affiliation":[{"name":"Department of Cardiology Barzilai Medical Center Ashkelon Israel"},{"name":"The Faculty of Medicine Ben\u2010Gurion University Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0625-7937","authenticated-orcid":false,"given":"Leor","family":"Perl","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petach Tikva Israel"},{"name":"Beilinson and Hasharon Hospitals, The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3513-6464","authenticated-orcid":false,"given":"Enrique","family":"Gallego\u2010Colon","sequence":"additional","affiliation":[{"name":"Department of Cardiology Barzilai Medical Center Ashkelon Israel"},{"name":"The Faculty of Medicine Ben\u2010Gurion University Beer\u2010Sheva Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aryel","family":"Furman","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petach Tikva Israel"},{"name":"Beilinson and Hasharon Hospitals, The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamir","family":"Bental","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petach Tikva Israel"},{"name":"Beilinson and Hasharon Hospitals, The Faculty of Medicine Tel Aviv University Tel Aviv Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amos","family":"Levi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Rabin Medical Center Petach Tikva Israel"},{"name":"Beilinson and Hasharon Hospitals, The Faculty of Medicine Tel Aviv University Tel Aviv 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