{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:09:51Z","timestamp":1758931791415,"version":"3.44.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T00:00:00Z","timestamp":1734220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Right ventricular\u2010to\u2010pulmonary artery (RV\u2010PA) coupling is an important predictor of long\u2010term survival following transcatheter edge\u2010to\u2010edge repair. However, its impact on survival in patients undergoing indirect mitral annuloplasty is unknown. The study aimed to assess the impact of baseline RV\u2010PA coupling on survival following indirect mitral annuloplasty in heart failure patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients were classified according to baseline RV\u2010PA coupling: TAPSE (tricuspid annular plane systolic excursion)\/PASP (pulmonary artery systolic pressure) &gt;\u20090.55 (group 1), \u2264\u20090.55\u2009\u2265\u20090.32 (group 2) and \u2264\u20090.32 (group 3). Clinical follow\u2010up and RV function were assessed 3 and 12 months following indirect annuloplasty.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A TAPSE\/PASP\u2009&gt;\u20090.55 was found in 19 patients, while 47 patients showed a TAPSE\/PASP\u2009\u2264\u20090.55\u2009&gt;\u20090.32 and 26 a TAPSE\/PASP\u2009\u2264\u20090.32. A significant reduction in vena contracta and regurgitant volume compared to baseline was found in all groups at 3\u2010months and 12\u2010months follow\u2010up. One\u2010year mortality was significantly increased in group 3 compared to the other groups (group 1: 0.95, group 2: 0.91, group 3: 0.77; Log\u2010Rank test <jats:italic>p<\/jats:italic>\u2009=\u20090.018). In groups 2 and 3 the TAPSE\/PASP significantly improved during the 12\u2010months follow\u2010up, while it remained unchanged in group 1 (group 1: baseline\u2009=\u20090.71\u2009\u00b1\u20090.03, 12\u2010months\u2009=\u20090.67\u2009\u00b1\u20090.01; group 2: baseline\u2009=\u20090.43\u2009\u00b1\u20090.06, 12\u2010months: 0.56\u2009\u00b1\u20090.04; group 3: baseline\u2009=\u20090.25\u2009\u00b1\u20090.06, 12\u2010months: 0.4\u2009\u00b1\u20090.03; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>RV\u2010PA uncoupling before indirect mitral annuloplasty is associated with poor survival. However, Carillon device implantation improved right heart function and RV\u2010PA coupling in patients with severe RV dysfunction at baseline. Therefore, Carillon device implantation can be a valuable option for transcatheter treatment of patients with FMR and right heart failure.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31340","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T01:39:22Z","timestamp":1734313162000},"page":"566-576","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of Right Ventricular to Pulmonary Artery Coupling on Survival Following Indirect Mitral Annuloplasty"],"prefix":"10.1002","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8789-9092","authenticated-orcid":false,"given":"Dennis","family":"Rottl\u00e4nder","sequence":"first","affiliation":[{"name":"Department of Cardiology Krankenhaus Porz am Rhein Cologne Germany"},{"name":"Department of Cardiology Faculty of Health, School of Medicine, Witten Witten\/Herdecke University Witten Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milad","family":"Golabkesh","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; Vascular Center, Rheinland Klinikum Neuss Neuss Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubertus","family":"Degen","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; Vascular Center, Rheinland Klinikum Neuss Neuss Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dimitrios","family":"Barlagiannis","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; Vascular Center, Rheinland Klinikum Neuss Neuss Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alev","family":"\u00d6g\u00fctc\u00fc","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; Vascular Center, Rheinland Klinikum Neuss Neuss Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Saal","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; Vascular Center, Rheinland Klinikum Neuss Neuss Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Haude","sequence":"additional","affiliation":[{"name":"Department of Cardiology Heart &amp; 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