{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T20:10:37Z","timestamp":1778875837800,"version":"3.51.4"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T00:00:00Z","timestamp":1734048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Optical coherence tomography (OCT) and intravascular ultrasound (IVUS) are adjunctive intracoronary imaging modalities used to optimize coronary stent implantation. However, the impact of OCT versus IVUS on clinical outcomes and periprocedural complications is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To perform a meta\u2010analysis of all vetted randomized controlled trials comparing OCT\u2010guided versus IVUS\u2010guided percutaneous coronary intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We queried MEDLINE, Cochrane Library, Scopus, and\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/clinicalTrials.gov\">clinicalTrials.gov<\/jats:ext-link>\n                      databases from their commencement to February 2024 for all randomized controlled trials that compared OCT\u2010guided versus IVUS\u2010guided percutaneous coronary interventions. The primary endpoint was major adverse periprocedural events (MAPE), a composite of stent thrombosis (ST), distal embolization (DE), and distal edge dissection (DED) at 30 days. The secondary endpoints included ST, DE, DED, major adverse cardiac events (MACE)\u2014(a composite of cardiac death, target vessel myocardial infarction TVMI], and target vessel revascularization [TVR]), all\u2010cause mortality, cardiac death, TVMI, TVR, and nonfatal stroke at 1 year. The odds ratio (OR) with a 95% confidence interval (CI) was analyzed using a random\u2010effect model.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Seven randomized controlled trials were included in the analysis, and 4446 patients were enrolled. OCT was associated with lower MAPE (OR: 0.65, CI: 0.47\u20130.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.01) compared to IVUS. ST, DE, and DED were similar between OCT and IVUS at 30 days. There were no significant differences in MACE (OR: 0.86, CI: 0.64\u20131.16,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.32), all\u2010cause mortality (OR: 0.83, CI: 0.42\u20131.66,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.60), Cardiac death (OR:0.62, CI: 0.20\u20131.89,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.40), TVMI (OR: 0.69, CI: 0.33\u20131.46,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.33), TVR, (OR: 1.09, CI: 0.70\u20131.71,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.70), and Nonfatal stroke (OR: 1.82, CI: 0.67\u20134.95,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.24) 1 year following the index procedure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Optical coherence tomographic\u2010guided PCI was associated with lower MAPE, defined as a composite of ST, DE, and DED, compared to IVUS\u2010guided PCI at 30 days of the index procedure. However, there was no difference in overall MACE, TVMI, TVR, and nonfatal stroke at 1 year.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31353","type":"journal-article","created":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T06:09:12Z","timestamp":1734070152000},"page":"532-540","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes Following Optical Coherence Tomographic Versus Intravascular Ultrasound\u2010Guided Percutaneous Coronary Intervention: A Meta\u2010Analysis of Randomized Controlled Trials"],"prefix":"10.1002","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3891-5073","authenticated-orcid":false,"given":"Sheriff N.","family":"Dodoo","sequence":"first","affiliation":[{"name":"Northeast Georgia Medical Center, Georgia Heart Institute Gainesville Georgia 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