{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T14:39:07Z","timestamp":1754145547386,"version":"3.41.2"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T00:00:00Z","timestamp":1736208000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>Transcatheter mitral valve replacement (TMVR) may emerge as a surgical alternative for high\u2010risk patients with severe mitral annular calcification (MAC), yet several questions remain to be addressed. We present the case of a 67\u2010year\u2010old high\u2010risk female patient with severe MAC (MAC score\u2009=\u20098) and mitral stenosis (effective orifice area\u2009=\u2009121.3\u2009mm<jats:sup>2<\/jats:sup>). To avoid conventional high\u2010risk surgery, we opted to perform the TMVR using the novel Mi\u2010thos system via the transapical approach. We utilized a patient\u2010specific three\u2010dimensional printed model derived by preprocedural computed tomography angiography data to assess the feasibility of the novel device and to guide the operation, mitigating potential challenges. The successful outcome of the guided procedure led to symptomatic improvement in the patient. This case represents the first experience with the novel Mi\u2010thos system for TMVR in a patient with severe MAC. Guided by a patient\u2010specific three\u2010dimensional printed model, the dedicated transcatheter heart valve may be a feasible and safe option for high\u2010risk patients with severe MAC.<\/jats:p>","DOI":"10.1002\/ccd.31405","type":"journal-article","created":{"date-parts":[[2025,1,7]],"date-time":"2025-01-07T03:10:07Z","timestamp":1736219407000},"page":"855-860","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First Experience With a Novel Self\u2010Expandable Valve for Mitral Annular Calcification Guided by Three\u2010Dimensional Printing"],"prefix":"10.1002","volume":"105","author":[{"given":"Yiwei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Xijing Hospital Air Force Medical University Xi'an Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuliang","family":"Ma","sequence":"additional","affiliation":[{"name":"Tie Yi High School International Curriculum Center Xi'an Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Xijing Hospital Air Force Medical University Xi'an Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2059-1912","authenticated-orcid":false,"given":"Jian","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Xijing Hospital Air Force Medical University Xi'an Shaanxi China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,1,7]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2010.08.072"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn544"},{"issue":"6","key":"e_1_2_13_4_1","first-page":"624","article-title":"Surgery for Non\u2010Rheumatic Calcific Mitral Stenosis","volume":"20","author":"Vohra H. A.","year":"2011","journal-title":"Journal of Heart Valve Disease"},{"issue":"6","key":"e_1_2_13_5_1","article-title":"Caseous Calcification of the Mitral Annulus: A Role for Surgery","volume":"109","author":"Chauvette V.","year":"2020","journal-title":"Annals of Thoracic Surgery"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.08.030"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(95)70055-2"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5223(03)00081-3"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.10.099"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.054"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.07.069"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd10080339"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytad434"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2020.03.013"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30926"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.07.007"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T05:19:06Z","timestamp":1752729546000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,7]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/ccd.31405"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31405","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"type":"print","value":"1522-1946"},{"type":"electronic","value":"1522-726X"}],"subject":[],"published":{"date-parts":[[2025,1,7]]},"assertion":[{"value":"2024-08-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}