{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T17:40:50Z","timestamp":1791999650419,"version":"4.4.0"},"reference-count":29,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Currently, there remains a paucity of research on the deformation and valve function of transcatheter heart valves (THV) in patients with aortic regurgitation (AR) following transcatheter aortic valve replacement (TAVR). This study aimed to thoroughly explore the correlation between THV deformation and postoperative hemodynamics in these patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this study, we assessed 39 AR patients treated with the J\u2010Valve THV system during TAVR. We utilized postoperative cardiac\u2010enhanced computed tomography angiography (CTA) to examine the extent of stent deformation, correlating these measurements with concurrent echocardiographic data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among patients with AR, the J\u2010Valve exhibited three distinct configurations: rectangular, trapezoidal, and inverted trapezoidal shapes. The rectangular configuration showed a trend toward a larger effective orifice area (EOA) compared to the trapezoidal and inverted trapezoidal configurations (rectangular: 2.20\u2009\u00b1\u20090.11\u2009cm\u00b2, trapezoidal: 1.88\u2009\u00b1\u20090.08\u2009cm\u00b2, inverted trapezoidal: 2.04\u2009\u00b1\u20090.08\u2009cm\u00b2; <jats:italic>p<\/jats:italic>\u2009=\u20090.068). Stratified analysis of the degree of inclined commissural posts indicated that THVs with all three commissural angles\u2009&lt;\u20095\u00b0 exhibited the highest standard EOA (sEOA). An increase in the number and degree of inclined commissural posts correlated with a decrease in sEOA. Furthermore, a higher EOA was observed when the expansion in the mid and transition level exceeded 80%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>During the TAVR procedure, ensuring sufficient expansion in the mid and transition level of the stent, maintaining the stent in a rectangular configuration, and avoiding tilting of the commissural posts contribute to achieving favorable postoperative hemodynamics.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31421","type":"journal-article","created":{"date-parts":[[2025,1,27]],"date-time":"2025-01-27T07:50:27Z","timestamp":1737964227000},"page":"1056-1066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Image\u2010Based Analysis of Correlation Between Valve Stent Deformation and Valve Function in Transcatheter Aortic Valve Replacement"],"prefix":"10.1002","volume":"105","author":[{"given":"Min","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University Nanjing Jiangsu China"},{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University Nanjing Jiangsu China"},{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuchun","family":"li","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haitao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Peking Union Medical College &amp; Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6499-1972","authenticated-orcid":false,"given":"Dongjin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University Nanjing Jiangsu China"},{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital Nanjing Jiangsu China"},{"name":"Department of Cardiac Surgery Nanjing Drum Tower Hospital, Peking Union Medical College &amp; Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College Nanjing Jiangsu China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103510"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.050"},{"issue":"5","key":"e_1_2_10_4_1","article-title":"2020 ACC\/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"143","author":"Otto C. 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