{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T04:03:06Z","timestamp":1749787386355,"version":"3.41.0"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Myeloproliferative neoplasms (MPN) are associated with an increased cardiovascular risk including acute coronary syndrome. However, there is a lack of comprehensive data regarding the rate of percutaneous coronary intervention (PCI), as well as the in\u2010hospital characteristics and outcomes for MPN patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aims<\/jats:title><jats:p>We aimed to evaluate the temporal trends and outcomes of PCI among patients with MPN.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods and Results<\/jats:title><jats:p>The National Inpatient Sample database from 2016 to 2020 was queried to identify all PCI hospitalizations. Temporal trends and outcomes of patients with and without MPN following PCI were analyzed. Propensity score matching (PSM) was implemented to compare outcomes between MPN and non\u2010MPN groups. 2,237,210 PCI hospitalizations with 7560 (0.27%) patients with MPN were included in this study. Throughout the study period, the prevalence of MPN among PCI admissions remained stable (p\u2010value for trend\u2009=\u20090.12). Within the MPN subgroup, essential thrombocythemia (ET) was the predominant condition (53.2). Patients with MPN had higher prevalence of cardiovascular comorbidities than non\u2010MPN patients. Following PSM, MPNs were significantly associated with a higher risk of blood transfusions (OR: 1.66, 95% CI: 1.22\u22122.24, <jats:italic>p<\/jats:italic>\u2009=\u20090.001) and AKI (OR: 1.39, 95% CI: 1.17\u22121.65, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). In contrast, the risk of in\u2010hospital mortality (OR: 1.18, 95% CI: 0.83\u22121.69, <jats:italic>p<\/jats:italic>\u2009=\u20090.354 and bleeding (OR: 1.43, 95% CI: 0.90\u22122.27, <jats:italic>p<\/jats:italic>\u2009=\u20090.127) did not significantly differ between the two groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study demonstrated that while the prevalence of MPN among patients undergoing PCI remained stable, those with MPN faced higher risks of bleeding, blood transfusion and acute kidney injury. Further research is warranted to explore the underlying reasons for these increased risks and to improve outcomes in this high\u2010risk group.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ccd.31489","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T12:25:02Z","timestamp":1741868702000},"page":"1535-1544","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Trends and Outcomes Following Percutaneous Coronary Intervention in Patients With Myeloproliferative Neoplasms: Insights From National Database"],"prefix":"10.1002","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8557-9880","authenticated-orcid":false,"given":"Song Peng","family":"Ang","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Rutgers Health\/Community Medical Center Toms River New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4636-0493","authenticated-orcid":false,"given":"Jia Ee","family":"Chia","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Texas Tech University Health Sciences Center El Paso Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7953-335X","authenticated-orcid":false,"given":"Chayakrit","family":"Krittanawong","sequence":"additional","affiliation":[{"name":"HumanX  Delaware USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert N.","family":"Piana","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Department of Medicine Vanderbilt University Medical Center Nashville Tennessee"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6302-9925","authenticated-orcid":false,"given":"Kwan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7118-2302","authenticated-orcid":false,"given":"Chadi","family":"Ayoub","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Mayo Clinic Phoenix Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"JR Exequiel","family":"Pineda","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine University of Arizona Tucson Arizona USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1864-1490","authenticated-orcid":false,"given":"David","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine New York Presbyterian Queens New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5131-3694","authenticated-orcid":false,"given":"Debabrata","family":"Mukherjee","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine Texas Tech University Health Sciences Center El Paso Texas USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,13]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-03-643544"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1406186"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20009"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.05277.x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2022.04.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001123"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurjpc\/zwae019"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.1998.00314.x"},{"issue":"6","key":"e_1_2_10_10_1","first-page":"397","article-title":"Myocardial Infarction as a Thrombotic Complication of Essential Thrombocythemia and Polycythemia Vera","volume":"16","author":"Posfai E.","year":"2016","journal-title":"The Anatolian Journal of Cardiology"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/09537104.2019.1665640"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2083-18"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000019288"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.14740\/jmc3388"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccao.2023.03.014"},{"key":"e_1_2_10_16_1","unstructured":"HCUP National Inpatient Sample (NIS). 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