{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T07:05:05Z","timestamp":1771225505065,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T00:00:00Z","timestamp":1745366400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Acute coronary syndrome\u2010cardiogenic shock (ACS\u2010CS) confers a 30\u2010day mortality rate of ~50%. A simple bed\u2010side risk score for 30\u2010day all\u2010cause mortality may aid in rapid prognostication in these high\u2010risk patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed data from consecutive patients with ACS\u2010CS enrolled in the Victorian Cardiac Outcomes Registry (VCOR), a state\u2010wide procedure\u2010based clinical quality registry, between 2013 and 2021. Internal validation was performed in 1000 bootstrapped samples to derive variables that were in &gt;\u200960% of models for the prediction of 30\u2010day mortality. Model performance was evaluated using C\u2010statistic, and Hosmer Lemeshow (HL) statistic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 1564 patients with ACS\u2010CS undergoing percutaneous coronary intervention (PCI), 1403 presented with ST\u2010elevation myocardial infarction (STEMI) and 161 with non\u2010STEMI. Age was 66\u2009\u00b1\u200913 years, and 74% were males. In\u2010hospital and 30\u2010day mortality rates were 42% and 45%. Selected predictors of 30\u2010day mortality included age (odds ratio (OR) 1.4 [1.3, 1.6] per 10 year increase), female sex (OR 1.4 [1.1, 1.8]), diabetes (OR 1.5 [1.2, 2.0]), estimated glomerular filtration rate\u2009&lt;\u200930\u2009mL\/min\/1.73\u2009m\n                      <jats:sup>2<\/jats:sup>\n                      (OR 2.2 [1.3, 3.5]), &lt;60\u2009mL\/min\/1.73\u2009m\n                      <jats:sup>2<\/jats:sup>\n                      (OR 1.5 [1.1, 2.0], left ventricular ejection fraction\u2009&lt;\u200935% (OR 4.6 [3.5, 6.1]), out\u2010of\u2010hospital cardiac arrest (OR 2.3 [1.8, 3.1]), pre\u2010procedural intubation (OR 2.1 [1.6, 2.7], mechanical circulatory support (OR 1.5 [1.1, 2.1]), STEMI (OR 2.6 [1.7, 3.8]), and multivessel PCI (OR 1.5 [1.1, 2.1], all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Internal validation of 1000 bootstrapped samples resulted in 15 clinical and procedural variables, which demonstrated excellent fit and performance (C\u2010statistic = 0.8, HL\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.44) for the prediction of 30\u2010day mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A risk score incorporating only peri\u2010procedural (clinical and procedural) variables accurately stratified 30\u2010day mortality risk among patients with ACS\u2010CS who underwent PCI. Further studies are required to externally validate the VCOR ACS\u2010CS risk score, however, its simplicity potentially facilitates translation into clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31540","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:29:49Z","timestamp":1745461789000},"page":"303-316","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of an Acute Coronary Syndrome\u2010Cardiogenic Shock Risk Score for 30\u2010day Mortality From the Victorian Cardiac Outcomes Registry (VCOR ACS\u2010CS Risk Score)"],"prefix":"10.1002","volume":"106","author":[{"given":"Nicholas","family":"D'Elia","sequence":"first","affiliation":[{"name":"Western Health Department of Cardiology  Victoria Australia"},{"name":"Baker Heart and Diabetes Institute  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Vogrin","sequence":"additional","affiliation":[{"name":"Department of Medicine University of Melbourne  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela L.","family":"Brennan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine Centre of Cardiovascular Research &amp; Education in Therapeutics  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diem","family":"Dinh","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine Centre of Cardiovascular Research &amp; Education in Therapeutics  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Lefkovits","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine Centre of Cardiovascular Research &amp; Education in Therapeutics  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9173-3944","authenticated-orcid":false,"given":"Christopher M.","family":"Reid","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Preventive Medicine Centre of Cardiovascular Research &amp; Education in Therapeutics  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dion","family":"Stub","sequence":"additional","affiliation":[{"name":"Western Health Department of Cardiology  Victoria Australia"},{"name":"Department of Epidemiology and Preventive Medicine Centre of Cardiovascular Research &amp; Education in Therapeutics  Victoria Australia"},{"name":"Department of Cardiology Alfred Hospital  Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason","family":"Bloom","sequence":"additional","affiliation":[{"name":"Baker Heart and Diabetes Institute  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