{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:26:48Z","timestamp":1787318808021,"version":"build-2736575974"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T00:00:00Z","timestamp":1748304000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Transcatheter aortic valve implantation (TAVI) has changed the treatment of aortic stenosis. The Myval transcatheter heart valve (THV), a novel balloon\u2010expandable THV, has shown promising outcomes. Our aim is to compare the comparative safety and effectiveness of Myval THV against established THVs, such as Sapien and Evolut. A systematic review and meta\u2010analysis was conducted, comparing the Myval THV with other contemporary THVs. Primary endpoints were periprocedural, 30\u2010day and 1\u2010year all\u2010cause mortality. Seven studies involving 3106 patients (1027 Myval; 2079 other THVs) were included. No significant differences were observed in the primary endpoints. Myval demonstrated higher procedural success (RR: 1.04, 95% CI: 1.01\u20131.07,\n                    <jats:italic>I<\/jats:italic>\n                    \u00b2\u2009=\u200929%) and lower rates of permanent pacemaker implantation (PPI) during the index hospitalization (RR: 0.57, 95% CI: 0.36\u20130.92,\n                    <jats:italic>I<\/jats:italic>\n                    \u00b2\u2009=\u200923%) and 30\u2010days (RR: 0.60, 95% CI: 0.40\u20130.89,\n                    <jats:italic>I<\/jats:italic>\n                    \u00b2\u2009=\u200943%), compared to other THV. At 30\u2010day, Myval was associated with lower rates of moderate or severe transvalvular aortic regurgitation (RR: 0.33, 95% CI: 0.11\u20130.98,\n                    <jats:italic>I<\/jats:italic>\n                    \u00b2\u2009=\u200957%) and minor vascular complications (RR: 0.45, 95% CI: 0.23\u20130.90,\n                    <jats:italic>I<\/jats:italic>\n                    \u00b2\u2009=\u20090%). When compared to self\u2010expandable THV, Myval was associated with higher procedural and device success, higher early safety, lower risk for PPI, minor vascular complications and at least moderate transvalvular AR. When compared to Sapien, procedural success and risk for in\u2010hospital PPI was borderline higher and lower in favor of Myval, respectively. The Myval THV demonstrates comparable safety and effectiveness to contemporary THVs, with advantages in procedural success, PPI, and vascular complications.\n                  <\/jats:p>","DOI":"10.1002\/ccd.31611","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T06:35:07Z","timestamp":1748327707000},"page":"820-829","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Effectiveness and Safety of Myval Versus Other Transcatheter Valves in Patients Undergoing TAVI: A Meta\u2010Analysis"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2616-7952","authenticated-orcid":false,"given":"Anastasios","family":"Apostolos","sequence":"first","affiliation":[{"name":"Unit of Structural Heart Diseases, First Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippocration General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0995-7015","authenticated-orcid":false,"given":"Nikolaos","family":"Ktenopoulos","sequence":"additional","affiliation":[{"name":"Unit of Structural Heart Diseases, First Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippocration General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0022-0332","authenticated-orcid":false,"given":"Maria","family":"Drakopoulou","sequence":"additional","affiliation":[{"name":"Unit of Structural Heart Diseases, First Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippocration General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfonso","family":"Ielasi","sequence":"additional","affiliation":[{"name":"U.O. Cardiologia Ospedaliera IRCCS Ospedale Galeazzi Sant'Ambrogio Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios","family":"Panoulas","sequence":"additional","affiliation":[{"name":"Royal Brompton and Harefield Hospitals Guy's and St Thomas' NHS Foundation Trust London UK"},{"name":"National Heart and Lung Institute Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Baumbach","sequence":"additional","affiliation":[{"name":"Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute Queen Mary University of London and Barts Heart Centre London UK"},{"name":"Cleveland Clinic London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Tsioufis","sequence":"additional","affiliation":[{"name":"Unit of Structural Heart Diseases, First Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippocration General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9636-1104","authenticated-orcid":false,"given":"Patrick","family":"Serruys","sequence":"additional","affiliation":[{"name":"Department of Cardiology, School of Medicine University of Galway Galway Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2946-344X","authenticated-orcid":false,"given":"Konstantinos","family":"Toutouzas","sequence":"additional","affiliation":[{"name":"Unit of Structural Heart Diseases, First Department of Cardiology, Medical School National and Kapodistrian University of Athens, Hippocration General Hospital of Athens Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,27]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccl.2019.09.003"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac803"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-023-00862-6"},{"key":"e_1_2_10_5_1","volume-title":"Transcatheter Versus Surgical Aortic Valve Replacement in US Patients Younger Than 65 Years of Age, in: 104th Annual Meeting","author":"Bowdish 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