{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T07:02:23Z","timestamp":1771225343971,"version":"3.50.1"},"reference-count":13,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T00:00:00Z","timestamp":1749340800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T00:00:00Z","timestamp":1749340800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Hypereosinophilic syndrome (HES) is a rare hematologic disorder characterized by persistently elevated eosinophil counts, leading to organ involvement. While eosinophilic myocarditis and endocarditis are common manifestations, coronary artery spasm as a presenting feature of HES is rare. We present the case of a 41\u2010year\u2010old female with a 4\u2010year history of asthma and chronic sinusitis who presented with a 6\u2010month history of dizziness, headaches, and syncope. Despite normal brain CT and MRI, she was diagnosed with a patent foramen ovale (PFO) and underwent closure. However, her symptoms persisted, and she developed intermittent chest pain, which was relieved by nitrates. Further investigation revealed severe right coronary artery spasm, and HES was diagnosed after a comprehensive evaluation, including elevated eosinophil counts and eosinophilic infiltration in the colon. The patient was treated with prednisone, which led to normalization of eosinophil levels and resolution of her symptoms. Follow\u2010up over 3 months showed no recurrence of dizziness or chest pain, and eosinophil counts remained within the normal range. This case highlights the importance of considering HES in the differential diagnosis of refractory coronary spasm and the value of early corticosteroid treatment. It also emphasizes the need for careful patient selection when considering PFO closure, as the procedure did not alleviate the patient's symptoms.<\/jats:p>","DOI":"10.1002\/ccd.31673","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T01:50:58Z","timestamp":1749433858000},"page":"1255-1259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Coronary Artery Spasm as a Rare Manifestation of Hypereosinophilic Syndrome: A Case Report"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7553-5515","authenticated-orcid":false,"given":"Tengfei","family":"Zheng","sequence":"first","affiliation":[{"name":"State Key Laboratory for Innovation and Transformation of Luobing Theory; Key Laboratory of Cardiovascular Remodeling and Function Research of MOE, NHC, CAMS and Shandong Province; Department of Cardiology Qilu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Song","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Innovation and Transformation of Luobing Theory; Key Laboratory of Cardiovascular Remodeling and Function Research of MOE, NHC, CAMS and Shandong Province; Department of Cardiology Qilu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6229-4943","authenticated-orcid":false,"given":"Ming","family":"Zhong","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Innovation and Transformation of Luobing Theory; Key Laboratory of Cardiovascular Remodeling and Function Research of MOE, NHC, CAMS and Shandong Province; Department of Cardiology Qilu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8086-9096","authenticated-orcid":false,"given":"Xiao","family":"Meng","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Innovation and Transformation of Luobing Theory; Key Laboratory of Cardiovascular Remodeling and Function Research of MOE, NHC, CAMS and Shandong Province; Department of Cardiology Qilu Hospital of Shandong University Jinan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.27287"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14488"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2020-317202"},{"issue":"12","key":"e_1_2_6_5_1","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1136\/heartjnl-2018-314114","article-title":"Recurrent Myocardial Infarction in a 50\u2010Year\u2010Old Woman","volume":"105","author":"Mactier I.","year":"2019","journal-title":"Heart"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2018-225321"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa357"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytae247"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.0886-18"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.0930-22"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.05.014"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11195595"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2018.10.002"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.iac.2022.10.010"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31673","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.31673","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31673","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T06:03:23Z","timestamp":1771221803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31673"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,8]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ccd.31673"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31673","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,8]]},"assertion":[{"value":"2025-04-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}