{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:38:02Z","timestamp":1790354282961,"version":"4.1.0"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T00:00:00Z","timestamp":1749600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Even after complete revascularization (CR), patients with acute myocardial infarction (AMI) still face significant risks of adverse events, frequently linked to vulnerable plaque progression in nonsignificant stenosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To investigate the relationship between the radial wall strain (RWS) of nonsignificant stenosis lesions and major adverse cardiac events (MACE) in patients with AMI following CR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cohort study included patients with AMI who received CR of all culprit and non\u2010culprit lesions with diameter stenosis (DS%) &gt;\u200970% during index or staged percutaneous coronary intervention within 45 days, with at least one de novo native lesion (DS% of 30%\u221270%) for RWS analysis. The primary outcome was MACE comprising cardiovascular death, nonfatal myocardial infarction, unstable angina, and heart failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      During a median follow\u2010up of 3.6 years, 55 among 225 patients (24.4%) experienced MACE, mainly driven by unstable angina. Maximum RWS (RWS\n                      <jats:sub>max<\/jats:sub>\n                      ) was predictive of MACE with an area under the curve of 0.84 (95% CI: 0.78\u22120.90;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and an optimal cutoff &gt;\u200914.5%. In the multivariable Cox regression model, RWS\n                      <jats:sub>max<\/jats:sub>\n                      \u2009&gt;\u200914.5% was an independent predictor for MACE among patients with AMI after CR (HR: 8.06; 95% CI: 3.98\u221216.35;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). In patients with Murray law\u2010based quantitative flow ratio (\u03bcQFR)\u2009&gt;\u20090.8, the prognostic impact of RWS\n                      <jats:sub>max<\/jats:sub>\n                      on MACE was comparable to that observed in patients with \u03bcQFR\u2009&lt;\u20090.8 (P for interaction\u2009=\u20090.236).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among patients with AMI who received CR, a high\u2010strain pattern detected by RWS analysis in nonsignificant stenosis lesions was associated with a worse clinical outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31680","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T03:13:56Z","timestamp":1749611636000},"page":"1291-1300","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Prognostic Value of Plaque Radial Wall Strain Analysis in Patients With Acute Myocardial Infarction After Complete Revascularization"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0308-1228","authenticated-orcid":false,"given":"Shujie","family":"Hou","sequence":"first","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital Capital Medical University Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Beijing Anzhen Hospital Capital Medical University Beijing 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