{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T07:02:16Z","timestamp":1771225336653,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,6,19]],"date-time":"2025-06-19T00:00:00Z","timestamp":1750291200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data comparing clinical and hemodynamic outcomes of bioprosthetic valve fracturing (BVF) and \u201cstandard\u201d\u2010postdilatation during valve\u2010in\u2010valve transcatheter heart valve implantation (ViV\u2010TAVI) are lacking. The authors aimed to analyze hemodynamic and clinical outcomes of BVF compared to \u201cstandard\u201d\u2010postdilatation during ViV\u2010TAVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The REDUCE registry included patients who underwent ViV\u2010TAVI within a Perimount surgical aortic valve bioprosthesis (Edwards Lifesciences, USA). Procedures were categorized to no postdilatation, \u201cstandard\u201d\u2010postdilatation and BVF. Hemodynamic and clinical outcomes at 30 days were collected and compared. A linear regression model was built to predict mean aortic gradient after ViV\u2010TAVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 240 patients from six European sites were included. Median age was 78 years [IQR 70; 83], logistic EuroSCORE calculated 20.0%[IQR 12.2; 33.1] and 159 patients (66%) were male. One hundred fourty\u2010four Perimount valves (60%) had a true internal diameter (ID)\u2009\u2264\u200921\u2009mm. Self\u2010expanding valves (SEV) and ballon\u2010expandable valves (BEV) were used in 60% and 40% of cases, respectively. One hundred sixteen procedures (48%) were executed without postdilatation, in 88 procedures (37%) \u201cstandard\u201d\u2010postdilatation and in 36 procedures (15%) BVF was used. 30\u2010day survival was 93.3%. VARC\u20103 device success at 30 days was 71%. A multivariable regression analysis of the mean aortic gradient after ViV\u2010TAVI showed a significant association with surgical valve size (\u22120.84\u2009mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001; per 1\u2009mm surgical valve size increase), execution of postdilatation (\u22123.25\u2009mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007) and type of transcatheter heart valve (SEV: \u22127.31\u2009mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>When performing ViV\u2010TAVI within a Perimount surgical aortic bioprosthesis with a true ID\u2009\u2264\u200921\u2009mm, the hemodynamic valve performance is most optimal when implanting a SEV\u2010TAV and when postdilating the TAV\u2010in\u2010SAV complex. BVF did not result in superior hemodynamics compared to \u201cstandard\u201d\u2010postdilatation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31686","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:24:05Z","timestamp":1750379045000},"page":"1409-1420","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Bioprosthetic Valve Fracturing in Valve\u2010in\u2010Valve TAVI: Clinical and Echocardiographic Outcomes in Failing Perimount Aortic Bioprostheses\u2014A Multicenter Registry"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6886-3660","authenticated-orcid":false,"given":"Hendrik","family":"Ruge","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melchior","family":"Burri","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Schreyer","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teodora\u2010Cristiana","family":"Georgescu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derk","family":"Frank","sequence":"additional","affiliation":[{"name":"German Center for Cardiovascular Research (DZHK) partner side Hamburg\/Kiel\/L\u00fcbeck Kiel Germany"},{"name":"Department of Internal Medicine III, Cardiology and Critical Care University Hospital Schleswig\u2010Holstein, Campus Kiel Kiel Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0799-7478","authenticated-orcid":false,"given":"Won\u2010Keun","family":"Kim","sequence":"additional","affiliation":[{"name":"Med. Clinic I, Cardiology &amp; Angiology University of Giessen und Marburg GmbH Giessen Germany"},{"name":"Department of Cardiology Kerckhoff Heart Center Bad Nauheim Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ole","family":"de Backer","sequence":"additional","affiliation":[{"name":"The Heart Center, Rigshospitalet Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Beyer","sequence":"additional","affiliation":[{"name":"University Heart and Vascular Center Hamburg Hamburg German"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7304-6083","authenticated-orcid":false,"given":"Andreas","family":"Sch\u00e4fer","sequence":"additional","affiliation":[{"name":"University Heart and Vascular Center Hamburg Hamburg German"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3972-4642","authenticated-orcid":false,"given":"Chiara","family":"Fraccaro","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Science University Medical School of Padua, Interventional Cardiology Unit Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Tarantini","sequence":"additional","affiliation":[{"name":"Department of Cardiac, Thoracic and Vascular Science University Medical School of Padua, Interventional Cardiology Unit Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erion","family":"Xhepa","sequence":"additional","affiliation":[{"name":"Department of Cardiology, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Joner","sequence":"additional","affiliation":[{"name":"Department of Cardiology, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markus","family":"Krane","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Institute Insure, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"},{"name":"Department of Surgery, Division of Cardiac Surgery Yale School of Medicine New Haven USA"},{"name":"DZHK (German Center for Cardiovascular Research)\u2014partner site Munich Heart Alliance  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H\u00e9ctor Alfonso Alvarez","family":"Covarrubias","sequence":"additional","affiliation":[{"name":"Department of Cardiology, German Heart Center Munich, School of Medicine &amp; Health Technical University of Munich  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,6,19]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-21-00157"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.024848"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.008155"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.02.014"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2019.02.029"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa544"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.7246"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.02.057"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.10.028"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2017.04.007"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.117.005216"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-17-00245"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.859088"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2019.01.073"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-21-00254"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.653871"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2022.12.019"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/24748706.2021.1895456"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29755"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaa799"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2018.10.043"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.21037\/acs-2021-tviv-25"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-19-00939"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJ-D-22-00644"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31686","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.31686","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.31686","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T06:03:18Z","timestamp":1771221798000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.31686"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,19]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10.1002\/ccd.31686"],"URL":"https:\/\/doi.org\/10.1002\/ccd.31686","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,19]]},"assertion":[{"value":"2025-05-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}