{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T22:34:47Z","timestamp":1784846087023,"version":"3.55.0"},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Direct transcatheter aortic valve implantation (TAVI) approach is feasible and safe compared to predilatation\u2010TAVI. Certain clinical and computerized tomography (CT)\u2010based characteristics might indicate the need for balloon aortic valvuloplasty (BAV) before TAVI, especially with self\u2010expanding valves.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>We aimed to identify patients who require predilatation before TAVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p>\n                      We performed a retrospective, single\u2010center study between 2020 and 2024, enrolling 315 patients (predilatation\u2009=\u2009158 vs. direct\u2009=\u2009157) aged 81\u2009\u00b1\u20096 years, 43.5% male, with EuroSCORE II of 3.7\u2009\u00b1\u20092.9. The rate of predilatation increased over the study period and was performed more often in patients with higher velocity and pressure gradients on echocardiography, higher aortic valve calcium score on CT, bicuspid morphology, bigger aortic annulus anatomy, severe aortic cusp calcification, tortuous descending aorta (bend &gt;\u200960\n                      <jats:bold>\u00b0<\/jats:bold>\n                      ), and horizontal ascending aorta (angle &gt;\u200950\n                      <jats:bold>\u00b0<\/jats:bold>\n                      ). Direct implantation was performed more frequently in patients with permanent pacemaker, ischemic heart disease, concomitant significant aortic regurgitation, or alternative\u2010access TAVI. Regression analysis demonstrated that only the horizontal aorta was an independent predictor of predilatation (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.037). The rates of valve recapture, embolization, contrast use, procedure duration, hospital stay, inpatient death, stroke, significant paravalvular leak on postprocedural echocardiography, and new pacemaker implantation were not different between the groups. The rate of BARC\u2009\u2265\u20093 bleeding, mainly due to access\u2010site complications, was more frequent with direct\u2010TAVI compared to predilatation (6.4% vs. 0.6%;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.005).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Both predilatation and direct\u2010TAVI approaches can be safely performed in routine practice. Upfront selection of either approach based on the patient characteristics, echocardiography gradients, and CT anatomical features is recommended.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.31731","type":"journal-article","created":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T01:39:21Z","timestamp":1751420361000},"page":"1674-1681","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Balloon Aortic Valvuloplasty Prior to Self\u2010Expanding TAVI: The BAVSE\u2010TAVI Registry"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2688-6295","authenticated-orcid":false,"given":"Abdalazeem","family":"Ibrahem","sequence":"first","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"},{"name":"Centre for Health Services Research, School of Life and Medical Sciences University of Hertfordshire Hertfordshire 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Freeman Hospital Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Edwards","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3642-318X","authenticated-orcid":false,"given":"Mohaned","family":"Egred","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azfar","family":"Zaman","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Alkhalil","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0811-7679","authenticated-orcid":false,"given":"Mohamed","family":"Farag","sequence":"additional","affiliation":[{"name":"Cardiothoracic Department Freeman Hospital Newcastle Upon Tyne UK"},{"name":"Centre for Health Services Research, School of Life and Medical Sciences University of Hertfordshire Hertfordshire UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,1]]},"reference":[{"issue":"2","key":"e_1_2_9_2_1","first-page":"116","article-title":"Predilatation Prior to Transcatheter Aortic Valve Implantation: Is It Still a Prerequisite?","volume":"12","author":"Pagnesi M.","year":"2017","journal-title":"Interventional Cardiology 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