{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T06:08:05Z","timestamp":1778998085027,"version":"3.51.4"},"reference-count":24,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Vasoplegic syndrome (VS) is a common complication after cardiac surgery with cardiopulmonary bypass (CPB). The main pathophysiology mechanism of VS includes a systemic inflammatory response syndrome due to surgical trauma, release of pro\u2010inflammatory mediators caused by blood contact with foreign surfaces of heart\u2010lung machine (pump and tubing) and endothelial dysfunction due to loss of pulsatile flow. Preoperative use of angiotensin\u2010converting enzyme inhibitors and beta\u2010blockers, coronary surgery and longer duration of CPB increase the incidence of VS. VS is characterized by hypotension with high cardiac output and low systemic resistance; treatment includes fluid resuscitation and vasopressors. Current authors report a case of cardiac VS, unresponsive to conventional therapy and successfully treated with angiotensin II (ATII) and hemoadsorption therapy.<\/jats:p>","DOI":"10.1002\/ccd.31744","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T01:11:42Z","timestamp":1751591502000},"page":"1740-1745","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Severe Vasoplegic Syndrome Treated with Angiotensin II and Hemoadsorption Therapy after Cardiac Surgery"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7006-2627","authenticated-orcid":false,"given":"Matteo","family":"Lucchelli","sequence":"first","affiliation":[{"name":"S.C. Rianimazione E Anestesia Legnano, ASST Ovest Milanese Legnano Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Davide Tommaso","family":"Andreis","sequence":"additional","affiliation":[{"name":"S.C. 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