{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:29:23Z","timestamp":1787167763622,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Valve\u2010in\u2010valve (ViV) procedures are an established therapy. Self\u2010expanding (SE) supra\u2010annular transcatheter heart valves (THV) achieve superior hemodynamics compared to balloon\u2010expandable (BE) intra\u2010annular THV, but influence of stent design versus valve position remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study compares SE intra\u2010 and supra\u2010annular THV for aortic ViV procedures to further elucidate this topic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>From 05\/2022 to 11\/2023, 10 patients underwent ViV procedures with the SE intra\u2010annular Navitor valve. A control group of 22 patients treated with the SE supra\u2010annular Evolut R\/PRO valve during the same period was retrieved from our database. Data were retrospectively analyzed according to updated valve academic research consortium (VARC) 3 definitions. A subgroup analysis matched patients for true internal diameter (ID) and body mass index (BMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Postprocedural transvalvular gradients were similar between groups. No differences in rates of significant paravalvular leakage (PVL) were seen (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.131). No all\u2010cause mortality occurred in either group. Device success (study group, Navitor: 70 [7] vs. control group, Evolut: 90.1 [20];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.293), early safety (90 [9] vs. 86.4 [19];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000), permanent pacemaker implantation (PPI) (0 [0] vs. 9.1 [2];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000), and stroke (0 [0] vs. 4.5 [1];\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.000) were similar between groups. Procedure time was shorter for the study group (65.8\u2009\u00b1\u200927.9\u2009min vs. 145.7\u2009\u00b1\u200951.3\u2009min;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After matching for True ID and BMI these results persisted.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Intra\u2010 and supra\u2010annular THV showed similar clinical and hemodynamic outcomes in aortic ViV procedures. These findings highlight the applicability of SE intra\u2010annular THV for aortic ViV procedures.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70011","type":"journal-article","created":{"date-parts":[[2025,7,18]],"date-time":"2025-07-18T05:28:56Z","timestamp":1752816536000},"page":"1873-1882","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Comparison of Latest Generation Intra\u2010 and Supra\u2010Annular Self\u2010Expanding Transcatheter Heart Valves for Aortic Valve\u2010in\u2010Valve Procedures"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1159-9097","authenticated-orcid":false,"given":"Antonia Katharina","family":"St\u00f6tzel","sequence":"first","affiliation":[{"name":"Departments of Cardiovascular Surgery University Heart and Vascular Center Hamburg, University Hospital Hamburg Eppendorf Hamburg 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