{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T01:57:11Z","timestamp":1792979831825,"version":"4.5.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>To reduce complications associated with metal occluders, bioabsorbable occluders have been implanted for perimembranous ventricular septal defects (VSDs) via transthoracic approach. This study investigates the feasibility of echocardiography\u2010guided percutaneous closure of perimembranous VSDs in children using bioabsorbable occluders, along with its 1\u2010year follow\u2010up outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To evaluate the feasibility and 1\u2010year outcomes of echocardiography\u2010guided percutaneous closure of perimembranous VSDs using bioabsorbable occluders in children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between April 2023 and March 2024, consecutive children with perimembranous VSDs underwent percutaneous closure using bioabsorbable occluders under echocardiography guidance alone were enrolled. Procedural success was defined as percutaneous device implantation under sole ultrasound guidance with residual shunt\u2009\u2264\u20092\u2009mm and no severe in\u2010hospital complications. Preoperative, intraoperative, and follow\u2010up data were prospectively collected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study cohort comprised 14 children, including three with a subaortic rim\u2009\u2264\u20093\u2009mm and one with a distance of \u2264\u20091\u2009mm between the VSD and the tricuspid septal leaflet. All procedures were successful. Vascular access was via the femoral artery in six patients (42.9%) and femoral vein in eight patients (57.1%). No major complications occurred. A 2\u2009mm residual shunt was noted in one patient (7.1%) and remained unchanged during the follow\u2010up period. While new\u2010onset mild\/moderate tricuspid regurgitation occurred in three patients (21.4%), all cases showed improvement over time. At 1 year, no new onset aortic regurgitation or complete heart block were reported, and the occluders were largely absorbed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Percutaneous closure of perimembranous VSDs in children using bioabsorbable occluders under echocardiography guidance is feasible, with promising 1\u2010year outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70022","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T09:48:26Z","timestamp":1753350506000},"page":"2018-2025","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Percutaneous Ultrasound\u2010Guided Closure of Perimembranous Ventricular Septal Defects in Children Using Bioabsorbable Occluders\u2014Feasibility and 1\u2010Year Follow\u2010Up"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5148-3052","authenticated-orcid":false,"given":"Liu Liu","family":"Huang","sequence":"first","affiliation":[{"name":"Department of Cardiothoracic Surgery The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mai","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"De Cai","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Lan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo Xing","family":"Ling","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun Xiao","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bao Shi","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6550-5589","authenticated-orcid":false,"given":"Ji","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Ultrasound The First Affiliated Hospital of Guangxi Medical University Nanning Guangxi China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2023.04.027"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1420704"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.21037\/cdt-23-361"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(87)80254-1"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jet105"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2017.01.007"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.88.2.621"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.12.018"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.21037\/jtd.2018.08.03"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1281860"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-019-1687-0"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-020-01750-6"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2019.11.004"},{"issue":"3","key":"e_1_2_10_15_1","first-page":"478","article-title":"Perventricular Device Closure of Perimembranous Ventricular Septal Defect: Effectiveness of Symmetric and Asymmetric Occluders [J]","volume":"51","author":"Ou\u2010Yang W. 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