{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T07:00:31Z","timestamp":1771225231564,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Few studies have addressed the early healing pattern of ultrathin strut drug\u2010eluting stents implanted specifically for the treatment of acute myocardial infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>AIMS<\/jats:title>\n                    <jats:p>This study employed optical coherence tomography (OCT) to assess neointimal coverage and vascular healing following implantation of ultrathin biodegradable polymer\u2010coated sirolimus\u2010eluting stents (SES) in patients with ST\u2010segment elevation myocardial infarction (STEMI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The OCIMI study was a prospective, single\u2010center investigation of 23 STEMI patients treated with Supraflex Cruz SES (Sahajanand Medical Technologies Ltd., Surat, India) during primary PCI between September 2019 and June 2020. All patients underwent OCT imaging at 3\u2010month follow\u2010up, and images were analyzed at an independent core laboratory by analysts blinded to clinical and procedural data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At the 3\u2010month follow\u2010up, no clinical events were reported. The analyzed stent length was 28.4\u2009\u00b1\u200912.0\u2009mm, with a stent diameter of 2.70\u2009\u00b1\u20090.46\u2009mm and a reference lumen diameter of 2.46\u2009\u00b1\u20090.44\u2009mm. OCT demonstrated nearly complete stent strut coverage (99.94%), with uncovered struts observed in 0.06\u2009\u00b1\u20090.16% of total struts per stent. Incomplete stent apposition was present in 0.14\u2009\u00b1\u20090.37% of struts. The mean neointimal hyperplasia (NIH) area and thickness were 0.81\u2009\u00b1\u20090.40 mm\n                      <jats:sup>2<\/jats:sup>\n                      and 110\u2009\u00b1\u200940\u2009\u00b5m, respectively, with a mean NIH unevenness score of 1.74\u2009\u00b1\u20090.19.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Primary PCI performed with Supraflex Cruz SES demonstrated excellent early vascular healing at the 3\u2010month OCT follow\u2010up. The extremely low incidence of uncovered struts may have implications for abbreviated dual antiplatelet therapy in high\u2010bleeding risk STEMI patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70046","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T13:40:22Z","timestamp":1753450822000},"page":"2093-2100","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Early Vascular Response of a Biodegradable Polymer\u2010Coated Sirolimus\u2010Eluting Stent in Patients With ST\u2010Segment Elevation Myocardial Infarction\u2014The OCIMI Study"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9726-1359","authenticated-orcid":false,"given":"Atul","family":"Abhyankar","sequence":"first","affiliation":[{"name":"Shri B D Mehta Mahavir Heart Institute Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhargav","family":"Patel","sequence":"additional","affiliation":[{"name":"Shri B D Mehta Mahavir Heart Institute Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ankit","family":"Jain","sequence":"additional","affiliation":[{"name":"Shri B D Mehta Mahavir Heart Institute Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikas","family":"Patel","sequence":"additional","affiliation":[{"name":"Shri B D Mehta Mahavir Heart Institute Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5246-3328","authenticated-orcid":false,"given":"Yamunesh","family":"Patel","sequence":"additional","affiliation":[{"name":"Shri B D Mehta Mahavir Heart Institute Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kan","family":"Saito","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihiro","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiro","family":"Honda","sequence":"additional","affiliation":[{"name":"Stanford University Stanford California USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krishnankutty","family":"Sudhir","sequence":"additional","affiliation":[{"name":"Sahajanand Medical Technologies Limited Surat India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-018-1287-1"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.981688"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.4244\/EIJV10I12A247"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.11.004"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e5170"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30474-X"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.09.028"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000538964"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.5152\/AnatolJCardiol.2021.78291"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2300468"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32467-X"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.29371"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.2217\/fca-2019-0083"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs095"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.119.008869"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmg.2017.12.014"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hsr2.105"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12928-022-00862-2"},{"key":"e_1_2_11_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-019-3293-8"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-20-0264"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.895167"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.10.043"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/joic.12510"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.854398"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.144220"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn604"},{"issue":"4","key":"e_1_2_11_28_1","first-page":"306","article-title":"Vessel Healings After Stenting With Different Polymers in STEMI Patients","volume":"13","author":"Jin Q.\u2010H.","year":"2016","journal-title":"Journal of Geriatric Cardiology: JGC"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.787762"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.06.043"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2024.0804"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.31481"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.09.006"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx393"}],"container-title":["Catheterization and Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70046","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ccd.70046","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ccd.70046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T06:00:33Z","timestamp":1771221633000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ccd.70046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/ccd.70046"],"URL":"https:\/\/doi.org\/10.1002\/ccd.70046","archive":["Portico"],"relation":{},"ISSN":["1522-1946","1522-726X"],"issn-type":[{"value":"1522-1946","type":"print"},{"value":"1522-726X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"assertion":[{"value":"2025-04-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}