{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:55:20Z","timestamp":1783464920528,"version":"3.55.0"},"reference-count":54,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T00:00:00Z","timestamp":1754611200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cathet Cardio Intervent"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>For over a decade, transfemoral transcatheter aortic valve replacements (TF\u2010TAVR) have been performed at the University Hospital of Nancy. A minimalistic approach to TF\u2010TAVR, conducted without general anesthesia and entirely percutaneously in a catheterization suite (simplified approach), has been reported to be as safe and successful as the standard approach under general anesthesia in an operating room with surgical arterial cutdown. This study compares our initial experience of the simplified approach with the standard approach for TF\u2010TAVR.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>Assessing feasibility and safety of a simplified TAVR compared with the standard approach.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We included TF\u2010TAVR performed from April 2020 to December 2021, and compared the simplified versus standard approach (SIMP\u2010group\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200989 vs. STD\u2010group\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009347). The endpoints included co\u2010primary endpoints defined by VARC\u20103 (technical success at procedure exit, device success at discharge, and early safety at discharge), individual events during hospitalization, and mortality at 30 days and 1 year.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline characteristics showed more comorbidities in the SIMP\u2010group. There were no significant differences for mortality rates and for the three co\u2010primary endpoints between the two groups. Bleeding and vascular complications were higher in the STD\u2010group (7.9% vs. 17%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.036 and 6.7% vs. 16%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.031). ICU and overall hospital stays were shorter in the SIMP\u2010group (median 1 vs. 2 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01 and 4 vs. 6 days,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study suggests that the simplified approach for TF\u2010TAVR is as safe and successful as the standard approach, even for patients with greater comorbidities and operative risk. These findings could extend the simplified approach to younger, lower\u2010risk patients, optimizing hospital resource use and reducing waiting times for TAVR.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ccd.70084","type":"journal-article","created":{"date-parts":[[2025,8,8]],"date-time":"2025-08-08T10:14:55Z","timestamp":1754648095000},"page":"2454-2468","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Feasibility and Safety of Transfemoral Aortic Valve Replacement Using Local Anesthesia in the Catheterization Suite Versus General Anesthesia in the Operation Theater"],"prefix":"10.1002","volume":"106","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-1537-7615","authenticated-orcid":false,"given":"Guillaume","family":"Abadi\u00e9","sequence":"first","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre Adrien","family":"Metzdorf","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Lauria","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery and Transplantation, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2830-0171","authenticated-orcid":false,"given":"Jeanne","family":"Varlot","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen","family":"Elfarra","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery and Transplantation, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0370-935X","authenticated-orcid":false,"given":"Florian","family":"Eggenspieler","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3844-5692","authenticated-orcid":false,"given":"Juan\u2010Pablo","family":"Maureira","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery and Transplantation, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2454-6468","authenticated-orcid":false,"given":"Batric","family":"Popovic","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3849-9842","authenticated-orcid":false,"given":"Edoardo","family":"Camenzind","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University Hospital of Nancy University of Lorraine Nancy France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,8]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"Elodie Velzenberger for the french \u201cHigh Health Authority\u201d Rapport_TAVI November 2020 https:\/\/www.has-sante.fr\/upload\/docs\/application\/pdf\/2020-11\/rapport_tavis.pdf."},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.21037\/acs-2020-av-24"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.10.021"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.053"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)30073-3"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2020.12.007"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.046451"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2012.01.018"},{"key":"e_1_2_11_11_1","unstructured":"V.Falk P. 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